O37928 · O37928_FHV1

Function

Catalytic activity

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6-ubiquitinyl-[acceptor protein]-L-lysine.
    EC:2.3.2.27 (UniProtKB | ENZYME | Rhea)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functionligase activity
Molecular Functionmetal ion binding
Molecular Functionubiquitin protein ligase activity
Biological Processprotein monoubiquitination
Biological Processprotein polyubiquitination
Biological Processsymbiont-mediated perturbation of host ubiquitin-like protein modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    RING-type E3 ubiquitin transferase
  • EC number

Gene names

    • Name
      ICP0

Organism names

Accessions

  • Primary accession
    O37928

Proteomes

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain8-47RING-type
Compositional bias106-136Polar residues
Region106-140Disordered
Region237-314Disordered
Compositional bias260-276Acidic residues
Compositional bias277-314Polar residues
Compositional bias343-373Polar residues
Region343-488Disordered
Compositional bias422-444Basic and acidic residues
Compositional bias447-476Polar residues

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    498
  • Mass (Da)
    55,012
  • Last updated
    1998-01-01 v1
  • Checksum
    6BC58DED3B9C58C8
MADMGDHCPICLDPMNDLTFTMPCLHKFCYSCLSRWVGLNNKCPLCKTSVTSLIHSIEDDKIFEETKLYSPHREEEEYLDWDPFIWTEARRWANISLNSVRLENSTTVDTSGRPSDGAGNPTSTRPRDSTSTGLGFVPLTPDGGAGAPHLRPLVTWMNSWLLNYYNDETTASVMCGIVMDELCEHAFNSAALTRLLRPLLHTQTDLFVIRLLAEASQCVFPSTARTLRVSTGVQFLDDTEDDTSSDDESSSLATADLTDPEDTAYDDTDDSDDTETTISTDLSVGITTGIDDETRHSLNTQPELSTLPHGSSATNFAAPAESIQQNYPETNMEPLDLTLAHDTESSNENSTTVIALDGANNDRTNTTENTAVSYDDGRADPIVNTTVSSRYQKNEDDIRGVHDADGPPNTDSGSHNTPISVTPTDRKRKRPPSRWNERRSARLRGSPETFNLVSTPSTSNMTQRDSSTTAISHTRLQTTRRGRRRVSGPIVHIPNTRL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias106-136Polar residues
Compositional bias260-276Acidic residues
Compositional bias277-314Polar residues
Compositional bias343-373Polar residues
Compositional bias422-444Basic and acidic residues
Compositional bias447-476Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FJ478159
EMBL· GenBank· DDBJ
AAB80763.1
EMBL· GenBank· DDBJ
Genomic DNA
KR296657
EMBL· GenBank· DDBJ
ANG65561.1
EMBL· GenBank· DDBJ
Genomic DNA
MH027357
EMBL· GenBank· DDBJ
AVR53468.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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