O30108 · NFI_ARCFU
- ProteinEndonuclease V
- Genenfi
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids221 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Recognizes only deoxyinosine.
Catalytic activity
Cofactor
Temperature Dependence
Optimum temperature is 85 degrees Celsius.
Features
Showing features for binding site, site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | deoxyribonuclease V activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | RNA endonuclease activity, producing 5'-phosphomonoesters | |
Molecular Function | single-stranded RNA binding | |
Biological Process | DNA repair |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameEndonuclease V
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Archaeoglobi > Archaeoglobales > Archaeoglobaceae > Archaeoglobus
Accessions
- Primary accessionO30108
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000159684 | 1-221 | Endonuclease V | |||
Sequence: MLQMNLEELRRIQEEMSRSVVLEDLIPLEELEYVVGVDQAFISDEVVSCAVKLTFPELEVVDKAVRVEKVTFPYIPTFLMFREGEPAVNAVKGLVDDRAAIMVDGSGIAHPRRCGLATYIALKLRKPTVGITKKRLFGEMVEVEDGLWRLLDGSETIGYALKSCRRCKPIFISPGSYISPDSALELTRKCLKGYKLPEPIRIADKLTKEVKRELTPTSKLK |
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length221
- Mass (Da)24,872
- Last updated1998-01-01 v1
- Checksum69F5DA504644A45C
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE000782 EMBL· GenBank· DDBJ | AAB91100.1 EMBL· GenBank· DDBJ | Genomic DNA |