O27275 · COME_METTH

Function

function

Involved in the biosynthesis of the coenzyme M (2-mercaptoethanesulfonic acid). Catalyzes the decarboxylation of sulfopyruvate to sulfoacetaldehyde.

Catalytic activity

Cofactor

thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

Note: Binds 1 thiamine pyrophosphate per subunit.

Pathway

Cofactor biosynthesis; coenzyme M biosynthesis; sulfoacetaldehyde from phosphoenolpyruvate and sulfite: step 4/4.

GO annotations

AspectTerm
Molecular Functionsulfopyruvate decarboxylase activity
Molecular Functionthiamine pyrophosphate binding
Biological Processcoenzyme M biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Sulfopyruvate decarboxylase subunit beta
  • EC number

Gene names

    • Name
      comE
    • Ordered locus names
      MTH_1207

Organism names

Accessions

  • Primary accession
    O27275

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000908401-185Sulfopyruvate decarboxylase subunit beta

Proteomic databases

Interaction

Subunit

Heterododecamer composed of 6 subunits alpha and 6 subunits beta.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the TPP enzyme family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    185
  • Mass (Da)
    20,008
  • Last updated
    1998-01-01 v1
  • MD5 Checksum
    77549406B1E52B1DF8AF69E1121143A6
MMLERIEAIERITGVLEDELVICNLGFPSRELYSIRDSPRHFYMLGSMGMASSIGLGLALSQERRVVVLDGDGSILMNLGGLVTAAAQSPGNLIIVLLDNRCYATTGSQCTYADVIDLGAVAESMGFNVIRFADDLNFEQALAMDGPVFAHVPVKPGNADVPVIDLDAEEIIERFIKEVRGATED

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE000666
EMBL· GenBank· DDBJ
AAB85696.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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