O24474 · TPSD2_ABIGR

Function

function

Involved in defensive oleoresin formation in conifers in response to insect attack or other injury. Involved in monoterpene (C10) olefins biosynthesis.

Miscellaneous

The conserved 64-Arg-Arg-65 motif may play a role in the isomerization step of the terpenoid cyclization reaction sequence.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 3 Mg2+ or Mn2+ ions per subunit.
K+ (UniProtKB | Rhea| CHEBI:29103 )

Pathway

Terpene metabolism; oleoresin biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site378Mg2+ 1 (UniProtKB | ChEBI)
Binding site378Mg2+ 2 (UniProtKB | ChEBI)
Binding site382Mg2+ 1 (UniProtKB | ChEBI)
Binding site382Mg2+ 2 (UniProtKB | ChEBI)
Binding site530Mg2+ 3 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentchloroplast
Molecular Functionmagnesium ion binding
Molecular Functionmyrcene synthase activity
Biological Processditerpenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Myrcene synthase, chloroplastic
  • EC number
  • Alternative names
    • Aggmyr

Gene names

    • Name
      ag2
    • Synonyms
      AG2.2

Organism names

Accessions

  • Primary accession
    O24474

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for transit peptide, chain.

TypeIDPosition(s)Description
Transit peptide1-52Chloroplast
ChainPRO_000003362753-627Myrcene synthase, chloroplastic

Expression

Induction

By wounding.

Structure

Family & Domains

Features

Showing features for motif.

TypeIDPosition(s)Description
Motif378-382DDXXD motif

Domain

The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg2+.

Sequence similarities

Belongs to the terpene synthase family. Tpsd subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    627
  • Mass (Da)
    72,479
  • Last updated
    1998-01-01 v1
  • Checksum
    2E0DA492E0C971FD
MALVSISPLASKSCLRKSLISSIHEHKPPYRTIPNLGMRRRGKSVTPSMSISLATAAPDDGVQRRIGDYHSNIWDDDFIQSLSTPYGEPSYQERAERLIVEVKKIFNSMYLDDGRLMSSFNDLMQRLWIVDSVERLGIARHFKNEITSALDYVFRYWEENGIGCGRDSIVTDLNSTALGFRTLRLHGYTVSPEVLKAFQDQNGQFVCSPGQTEGEIRSVLNLYRASLIAFPGEKVMEEAEIFSTRYLKEALQKIPVSALSQEIKFVMEYGWHTNLPRLEARNYIDTLEKDTSAWLNKNAGKKLLELAKLEFNIFNSLQQKELQYLLRWWKESDLPKLTFARHRHVEFYTLASCIAIDPKHSAFRLGFAKMCHLVTVLDDIYDTFGTIDELELFTSAIKRWNSSEIEHLPEYMKCVYMVVFETVNELTREAEKTQGRNTLNYVRKAWEAYFDSYMEEAKWISNGYLPMFEEYHENGKVSSAYRVATLQPILTLNAWLPDYILKGIDFPSRFNDLASSFLRLRGDTRCYKADRDRGEEASCISCYMKDNPGSTEEDALNHINAMVNDIIKELNWELLRSNDNIPMLAKKHAFDITRALHHLYIYRDGFSVANKETKKLVMETLLESMLF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U87908
EMBL· GenBank· DDBJ
AAB71084.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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