O23614 · CTPA2_ARATH
- ProteinCarboxyl-terminal-processing peptidase 2, chloroplastic
- GeneCTPA2
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids515 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Variants
Variant ID(s) | Position(s) | Change | Description | Clinical significance | Provenance | ||
---|---|---|---|---|---|---|---|
tmp_4_9869531_A_T | 30 | L>M | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.26) Somatic: No Accession: 4:g.9869531A>T Codon: TTG/ATG Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869531A>T Locations: - p.Leu30Met (EnsemblPlants:AT4G17740.1) - c.88T>A (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9869526_C_A | 31 | W>C | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: 4:g.9869526C>A Codon: TGG/TGT Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869526C>A Locations: - p.Trp31Cys (EnsemblPlants:AT4G17740.1) - c.93G>T (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH11943137 | 33 | K>T | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.65) Somatic: No Accession: 4:g.9869521T>G Codon: AAA/ACA Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869521T>G Locations: - p.Lys33Thr (EnsemblPlants:AT4G17740.1) - c.98A>C (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH11943135 | 35 | P>A | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0.04) Somatic: No Accession: 4:g.9869516G>C Codon: CCT/GCT Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869516G>C Locations: - p.Pro35Ala (EnsemblPlants:AT4G17740.1) - c.103C>G (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9869503_G_A | 39 | S>L | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.48) Somatic: No Accession: 4:g.9869503G>A Codon: TCA/TTA Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869503G>A Locations: - p.Ser39Leu (EnsemblPlants:AT4G17740.1) - c.116C>T (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH11943114 | 43 | K>N | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.36) Somatic: No Accession: 4:g.9869490T>G Codon: AAA/AAC Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869490T>G Locations: - p.Lys43Asn (EnsemblPlants:AT4G17740.1) - c.129A>C (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH11943113 | 44 | F>C | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.11) Somatic: No Accession: 4:g.9869488A>C Codon: TTT/TGT Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869488A>C Locations: - p.Phe44Cys (EnsemblPlants:AT4G17740.1) - c.131T>G (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH14239948 | 47 | A>V | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.73) Somatic: No Accession: 4:g.9869479G>A Codon: GCT/GTT Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869479G>A Locations: - p.Ala47Val (EnsemblPlants:AT4G17740.1) - c.140C>T (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH02868309 | 50 | R>L | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.38) Somatic: No Accession: 4:g.9869470C>A Codon: CGT/CTT Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869470C>A Locations: - p.Arg50Leu (EnsemblPlants:AT4G17740.1) - c.149G>T (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH11943112 | 53 | I>N | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.44) Somatic: No Accession: 4:g.9869461A>T Codon: ATT/AAT Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869461A>T Locations: - p.Ile53Asn (EnsemblPlants:AT4G17740.1) - c.158T>A (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH06706843 | 58 | A>V | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.14) Somatic: No Accession: 4:g.9869446G>A Codon: GCA/GTA Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869446G>A Locations: - p.Ala58Val (EnsemblPlants:AT4G17740.1) - c.173C>T (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH11943110 | 59 | A>T | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.48) Somatic: No Accession: 4:g.9869444C>T Codon: GCA/ACA Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869444C>T Locations: - p.Ala59Thr (EnsemblPlants:AT4G17740.1) - c.175G>A (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9869429_C_T | 64 | V>M | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.14) Somatic: No Accession: 4:g.9869429C>T Codon: GTG/ATG Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869429C>T Locations: - p.Val64Met (EnsemblPlants:AT4G17740.1) - c.190G>A (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH11943108 | 74 | I>V | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.86) Somatic: No Accession: 4:g.9869399T>C Codon: ATC/GTC Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869399T>C Locations: - p.Ile74Val (EnsemblPlants:AT4G17740.1) - c.220A>G (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH11943107 | 87 | M>L | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.78) Somatic: No Accession: 4:g.9869360T>G Codon: ATG/CTG Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869360T>G Locations: - p.Met87Leu (EnsemblPlants:AT4G17740.1) - c.259A>C (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH11943106 | 90 | S>P | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.27) Somatic: No Accession: 4:g.9869351A>G Codon: TCT/CCT Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869351A>G Locations: - p.Ser90Pro (EnsemblPlants:AT4G17740.1) - c.268T>C (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9869339_A_G | 94 | F>L | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.51) Somatic: No Accession: 4:g.9869339A>G Codon: TTC/CTC Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869339A>G Locations: - p.Phe94Leu (EnsemblPlants:AT4G17740.1) - c.280T>C (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH06706841 | 100 | V>A | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0.01) Somatic: No Accession: 4:g.9869320A>G Codon: GTT/GCT Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869320A>G Locations: - p.Val100Ala (EnsemblPlants:AT4G17740.1) - c.299T>C (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9869317_G_C | 101 | A>G | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.38) Somatic: No Accession: 4:g.9869317G>C Codon: GCA/GGA Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869317G>C Locations: - p.Ala101Gly (EnsemblPlants:AT4G17740.1) - c.302C>G (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9869312_C_G | 103 | V>L | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.3) Somatic: No Accession: 4:g.9869312C>G Codon: GTT/CTT Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869312C>G Locations: - p.Val103Leu (EnsemblPlants:AT4G17740.1) - c.307G>C (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH00517622 | 163 | L>I | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.1) Somatic: No Accession: 4:g.9869036A>T Codon: TTA/ATA Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869036A>T Locations: - p.Leu163Ile (EnsemblPlants:AT4G17740.1) - c.487T>A (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9869009_C_T | 172 | E>K | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.08) Somatic: No Accession: 4:g.9869009C>T Codon: GAA/AAA Consequence type: missense Cytogenetic band: Genomic location: 4:g.9869009C>T Locations: - p.Glu172Lys (EnsemblPlants:AT4G17740.1) - c.514G>A (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH14239946 | 186 | D>G | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.1) Somatic: No Accession: 4:g.9868888T>C Codon: GAT/GGT Consequence type: missense Cytogenetic band: Genomic location: 4:g.9868888T>C Locations: - p.Asp186Gly (EnsemblPlants:AT4G17740.1) - c.557A>G (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9868855_T_C | 197 | K>R | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.14) Somatic: No Accession: 4:g.9868855T>C Codon: AAG/AGG Consequence type: missense Cytogenetic band: Genomic location: 4:g.9868855T>C Locations: - p.Lys197Arg (EnsemblPlants:AT4G17740.1) - c.590A>G (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH11943020 | 219 | P>L | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 4:g.9868702G>A Codon: CCC/CTC Consequence type: missense Cytogenetic band: Genomic location: 4:g.9868702G>A Locations: - p.Pro219Leu (EnsemblPlants:AT4G17740.1) - c.656C>T (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH11943019 | 220 | T>A | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.44) Somatic: No Accession: 4:g.9868700T>C Codon: ACT/GCT Consequence type: missense Cytogenetic band: Genomic location: 4:g.9868700T>C Locations: - p.Thr220Ala (EnsemblPlants:AT4G17740.1) - c.658A>G (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH11943016 | 246 | L>S | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.76) Somatic: No Accession: 4:g.9868621A>G Codon: TTA/TCA Consequence type: missense Cytogenetic band: Genomic location: 4:g.9868621A>G Locations: - p.Leu246Ser (EnsemblPlants:AT4G17740.1) - c.737T>C (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH14239913 | 278 | A>T | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.64) Somatic: No Accession: 4:g.9868417C>T Codon: GCA/ACA Consequence type: missense Cytogenetic band: Genomic location: 4:g.9868417C>T Locations: - p.Ala278Thr (EnsemblPlants:AT4G17740.1) - c.832G>A (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH11943000 | 282 | A>T | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (1) Somatic: No Accession: 4:g.9868405C>T Codon: GCG/ACG Consequence type: missense Cytogenetic band: Genomic location: 4:g.9868405C>T Locations: - p.Ala282Thr (EnsemblPlants:AT4G17740.1) - c.844G>A (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH11942999 | 289 | T>M | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.1) Somatic: No Accession: 4:g.9868383G>A Codon: ACG/ATG Consequence type: missense Cytogenetic band: Genomic location: 4:g.9868383G>A Locations: - p.Thr289Met (EnsemblPlants:AT4G17740.1) - c.866C>T (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9868378_G_T | 291 | L>I | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.17) Somatic: No Accession: 4:g.9868378G>T Codon: CTC/ATC Consequence type: missense Cytogenetic band: Genomic location: 4:g.9868378G>T Locations: - p.Leu291Ile (EnsemblPlants:AT4G17740.1) - c.871C>A (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH06706831 | 295 | T>M | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.16) Somatic: No Accession: 4:g.9868365G>A Codon: ACG/ATG Consequence type: missense Cytogenetic band: Genomic location: 4:g.9868365G>A Locations: - p.Thr295Met (EnsemblPlants:AT4G17740.1) - c.884C>T (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH00517619 | 297 | E>D | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.64) Somatic: No Accession: 4:g.9868287C>A Codon: GAG/GAT Consequence type: missense Cytogenetic band: Genomic location: 4:g.9868287C>A Locations: - p.Glu297Asp (EnsemblPlants:AT4G17740.1) - c.891G>T (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9868244_G_A | 312 | P>S | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.11) Somatic: No Accession: 4:g.9868244G>A Codon: CCT/TCT Consequence type: missense Cytogenetic band: Genomic location: 4:g.9868244G>A Locations: - p.Pro312Ser (EnsemblPlants:AT4G17740.1) - c.934C>T (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9868030_C_T | 353 | V>I | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.67) Somatic: No Accession: 4:g.9868030C>T Codon: GTC/ATC Consequence type: missense Cytogenetic band: Genomic location: 4:g.9868030C>T Locations: - p.Val353Ile (EnsemblPlants:AT4G17740.1) - c.1057G>A (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH11942942 | 373 | F>L | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.9) Somatic: No Accession: 4:g.9867892A>T Codon: TTT/TTA Consequence type: missense Cytogenetic band: Genomic location: 4:g.9867892A>T Locations: - p.Phe373Leu (EnsemblPlants:AT4G17740.1) - c.1119T>A (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH11942936 | 402 | A>S | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.09) Somatic: No Accession: 4:g.9867714C>A Codon: GCA/TCA Consequence type: missense Cytogenetic band: Genomic location: 4:g.9867714C>A Locations: - p.Ala402Ser (EnsemblPlants:AT4G17740.1) - c.1204G>T (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9867711_T_C | 403 | T>A | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.66) Somatic: No Accession: 4:g.9867711T>C Codon: ACC/GCC Consequence type: missense Cytogenetic band: Genomic location: 4:g.9867711T>C Locations: - p.Thr403Ala (EnsemblPlants:AT4G17740.1) - c.1207A>G (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH06706817 | 413 | K>R | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.23) Somatic: No Accession: 4:g.9867581T>C Codon: AAA/AGA Consequence type: missense Cytogenetic band: Genomic location: 4:g.9867581T>C Locations: - p.Lys413Arg (EnsemblPlants:AT4G17740.1) - c.1238A>G (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9867519_C_T | 434 | V>I | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.28) Somatic: No Accession: 4:g.9867519C>T Codon: GTT/ATT Consequence type: missense Cytogenetic band: Genomic location: 4:g.9867519C>T Locations: - p.Val434Ile (EnsemblPlants:AT4G17740.1) - c.1300G>A (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9867390_C_A | 450 | E>* | 1000Genomes | ||||
Consequence: stop gained Somatic: No Accession: 4:g.9867390C>A Codon: GAG/TAG Consequence type: stop gained Cytogenetic band: Genomic location: 4:g.9867390C>A Locations: - p.Glu450Ter (EnsemblPlants:AT4G17740.1) - c.1348G>T (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9867357_C_T | 461 | V>I | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.22) Somatic: No Accession: 4:g.9867357C>T Codon: GTT/ATT Consequence type: missense Cytogenetic band: Genomic location: 4:g.9867357C>T Locations: - p.Val461Ile (EnsemblPlants:AT4G17740.1) - c.1381G>A (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9867333_G_A | 469 | H>Y | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 4:g.9867333G>A Codon: CAC/TAC Consequence type: missense Cytogenetic band: Genomic location: 4:g.9867333G>A Locations: - p.His469Tyr (EnsemblPlants:AT4G17740.1) - c.1405C>T (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
ENSVATH11942869 | 488 | P>S | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.02) Somatic: No Accession: 4:g.9867174G>A Codon: CCG/TCG Consequence type: missense Cytogenetic band: Genomic location: 4:g.9867174G>A Locations: - p.Pro488Ser (EnsemblPlants:AT4G17740.1) - c.1462C>T (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9867140_T_G | 499 | K>T | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.06) Somatic: No Accession: 4:g.9867140T>G Codon: AAG/ACG Consequence type: missense Cytogenetic band: Genomic location: 4:g.9867140T>G Locations: - p.Lys499Thr (EnsemblPlants:AT4G17740.1) - c.1496A>C (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9867105_G_T | 511 | L>I | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.05) Somatic: No Accession: 4:g.9867105G>T Codon: CTA/ATA Consequence type: missense Cytogenetic band: Genomic location: 4:g.9867105G>T Locations: - p.Leu511Ile (EnsemblPlants:AT4G17740.1) - c.1531C>A (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: | |||||||
tmp_4_9867104_A_G | 511 | L>P | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.08) Somatic: No Accession: 4:g.9867104A>G Codon: CTA/CCA Consequence type: missense Cytogenetic band: Genomic location: 4:g.9867104A>G Locations: - p.Leu511Pro (EnsemblPlants:AT4G17740.1) - c.1532T>C (EnsemblPlants:AT4G17740.1) Source type: large scale study Cross-references: |