O23474 · PER40_ARATH

Function

function

Removal of H2O2, oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.

Miscellaneous

There are 73 peroxidase genes in A.thaliana.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 2 calcium ions per subunit.

Features

Showing features for site, active site, binding site.

TypeIDPosition(s)Description
Site86Transition state stabilizer
Active site90Proton acceptor
Binding site91Ca2+ 1 (UniProtKB | ChEBI)
Binding site94Ca2+ 1 (UniProtKB | ChEBI)
Binding site96Ca2+ 1 (UniProtKB | ChEBI)
Binding site98Ca2+ 1 (UniProtKB | ChEBI)
Binding site100Ca2+ 1 (UniProtKB | ChEBI)
Binding site187substrate
Binding site217Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue
Binding site218Ca2+ 2 (UniProtKB | ChEBI)
Binding site269Ca2+ 2 (UniProtKB | ChEBI)
Binding site272Ca2+ 2 (UniProtKB | ChEBI)
Binding site277Ca2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentextracellular region
Molecular Functionheme binding
Molecular Functionlactoperoxidase activity
Molecular Functionmetal ion binding
Biological Processhydrogen peroxide catabolic process
Biological Processresponse to oxidative stress

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Peroxidase 40
  • EC number
  • Short names
    Atperox P40

Gene names

    • Name
      PER40
    • Synonyms
      P40
    • ORF names
      dl4175w, FCAALL.329
    • Ordered locus names
      At4g16270

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    O23474
  • Secondary accessions
    • F4JLR5
    • Q53XE3
    • Q67ZY5

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, glycosylation, disulfide bond.

TypeIDPosition(s)Description
Signal1-21
ChainPRO_000002370622-348Peroxidase 40
Glycosylation26N-linked (GlcNAc...) asparagine
Disulfide bond59↔139
Disulfide bond92↔97
Disulfide bond145↔344
Glycosylation190N-linked (GlcNAc...) asparagine
Disulfide bond224↔256

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region170-189Disordered

Sequence similarities

Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    348
  • Mass (Da)
    37,460
  • Last updated
    2002-12-06 v2
  • Checksum
    1B438813818178E5
MKNLFNLFLMFFFAMPILSLSENPTNFSESCEDGSGETGSSFGIGFDLVLDFGLYRNSCPEAESIVYSWVETTVLEDPRMAASLLRLHFHDCFVNGCDASVLLDDTEGLVGEKTAPPNLNSLRGFEVIDSIKSDIESVCPETVSCADILAMAARDSVVVSGGPRWEVEVGRKDSRTASKQAATNGLPSPNSTVSTLISTFQNLGLSQTDMVALSGGHTLGKARCTSFTARLQPLQTGQPANHGDNLEFLESLQQLCSTVGPSVGITQLDLVTPSTFDNQYYVNLLSGEGLLPSDQALAVQDPGTRAIVETYATDQSVFFEDFKNAMVKMGGIPGGSNSEIRKNCRMIN

Sequence caution

The sequence BAD43424.1 differs from that shown. Reason: Erroneous initiation Extended N-terminus.
The sequence BAD43745.1 differs from that shown. Reason: Erroneous initiation Extended N-terminus.
The sequence CAB10406.1 differs from that shown. Reason: Erroneous gene model prediction
The sequence CAB78669.1 differs from that shown. Reason: Erroneous gene model prediction

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Z97340
EMBL· GenBank· DDBJ
CAB10406.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
AL161543
EMBL· GenBank· DDBJ
CAB78669.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CP002687
EMBL· GenBank· DDBJ
AEE83724.2
EMBL· GenBank· DDBJ
Genomic DNA
BT011747
EMBL· GenBank· DDBJ
AAS49110.1
EMBL· GenBank· DDBJ
mRNA
AK175661
EMBL· GenBank· DDBJ
BAD43424.1
EMBL· GenBank· DDBJ
mRNA Different initiation
AK175982
EMBL· GenBank· DDBJ
BAD43745.1
EMBL· GenBank· DDBJ
mRNA Different initiation

Genome annotation databases

Similar Proteins

Disclaimer

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