O23087 · ECA2_ARATH

Function

function

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to an endomembrane compartment.

Catalytic activity

Features

Showing features for binding site, active site.

110541002003004005006007008009001,000
TypeIDPosition(s)Description
Binding site321Ca2+ 2 (UniProtKB | ChEBI)
Binding site322Ca2+ 2 (UniProtKB | ChEBI)
Binding site324Ca2+ 2 (UniProtKB | ChEBI)
Binding site326Ca2+ 2 (UniProtKB | ChEBI)
Active site3684-aspartylphosphate intermediate
Binding site727Mg2+ (UniProtKB | ChEBI)
Binding site731Mg2+ (UniProtKB | ChEBI)
Binding site793Ca2+ 1 (UniProtKB | ChEBI)
Binding site796Ca2+ 1 (UniProtKB | ChEBI)
Binding site821Ca2+ 2 (UniProtKB | ChEBI)
Binding site824Ca2+ 1 (UniProtKB | ChEBI)
Binding site825Ca2+ 1 (UniProtKB | ChEBI)
Binding site825Ca2+ 2 (UniProtKB | ChEBI)
Binding site960Ca2+ 1 (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendoplasmic reticulum
Cellular Componentmembrane
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular Functionmetal ion binding
Molecular FunctionP-type calcium transporter activity
Biological Processcalcium ion transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Calcium-transporting ATPase 2, endoplasmic reticulum-type
  • EC number

Gene names

    • Name
      ECA2
    • Synonyms
      ACA5
    • ORF names
      A_TM018A10.4
    • Ordered locus names
      At4g00900

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    O23087

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-53Cytoplasmic
Transmembrane54-74Helical
Topological domain75-98Lumenal
Transmembrane99-118Helical
Topological domain119-262Cytoplasmic
Transmembrane263-282Helical
Topological domain283-312Lumenal
Transmembrane313-330Helical
Topological domain331-782Cytoplasmic
Transmembrane783-802Helical
Topological domain803-812Lumenal
Transmembrane813-833Helical
Topological domain834-853Cytoplasmic
Transmembrane854-876Helical
Topological domain877-949Lumenal
Transmembrane950-969Helical
Topological domain970-982Cytoplasmic
Transmembrane983-1001Helical
Topological domain1002-1016Lumenal
Transmembrane1017-1037Helical
Topological domain1038-1054Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000464061-1054Calcium-transporting ATPase 2, endoplasmic reticulum-type

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,054
  • Mass (Da)
    115,830
  • Last updated
    1998-01-01 v1
  • Checksum
    B0D7F7237A3496AF
MEEEKSFSAWSWSVEQCLKEYKTRLDKGLTSEDVQIRRQKYGFNELAKEKGKPLWHLVLEQFDDTLVKILLGAAFISFVLAFLGEEHGSGSGFEAFVEPFVIVLILILNAVVGVWQESNAEKALEALKEMQCESAKVLRDGNVLPNLPARELVPGDIVELNVGDKVPADMRVSGLKTSTLRVEQSSLTGEAMPVLKGANLVVMDDCELQGKENMVFAGTTVVNGSCVCIVTSIGMDTEIGKIQRQIHEASLEESETPLKKKLDEFGSRLTTAICIVCVLVWMINYKNFVSWDVVDGYKPVNIKFSFEKCTYYFKIAVALAVAAIPEGLPAVITTCLALGTRKMAQKNAIVRKLPSVETLGCTTVICSDKTGTLTTNQMSATEFFTLGGKTTTTRVFSVSGTTYDPKDGGIVDWGCNNMDANLQAVAEICSICNDAGVFYEGKLFRATGLPTEAALKVLVEKMGIPEKKNSENIEEVTNFSDNGSSVKLACCDWWNKRSKKVATLEFDRVRKSMSVIVSEPNGQNRLLVKGAAESILERSSFAQLADGSLVALDESSREVILKKHSEMTSKGLRCLGLAYKDELGEFSDYSSEEHPSHKKLLDPSSYSNIETNLIFVGVVGLRDPPREEVGRAIEDCRDAGIRVMVITGDNKSTAEAICCEIRLFSENEDLSQSSFTGKEFMSLPASRRSEILSKSGGKVFSRAEPRHKQEIVRMLKEMGEIVAMTGDGVNDAPALKLADIGIAMGITGTEVAKEASDMVLADDNFSTIVSAVAEGRSIYNNMKAFIRYMISSNVGEVISIFLTAALGIPECMIPVQLLWVNLVTDGPPATALGFNPADIDIMKKPPRKSDDCLIDSWVLIRYLVIGSYVGVATVGIFVLWYTQASFLGISLISDGHTLVSFTQLQNWSECSSWGTNFTATPYTVAGGLRTIAFENNPCDYFTLGKVKPMTLSLTVLVAIEMFNSLNALSEDNSLLTMPPWRNPWLLVAMTVSFALHCVILYVPFLANVFGIVPLSFREWFVVILVSFPVILIDEALKFIGRCRRTRIKKKIKTM

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJ132387
EMBL· GenBank· DDBJ
CAA10659.1
EMBL· GenBank· DDBJ
mRNA
AF013294
EMBL· GenBank· DDBJ
AAB62850.1
EMBL· GenBank· DDBJ
Genomic DNA
AL161472
EMBL· GenBank· DDBJ
CAB80899.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002687
EMBL· GenBank· DDBJ
AEE81953.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002687
EMBL· GenBank· DDBJ
ANM67918.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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