O22765 · TRPA1_ARATH

Function

function

The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate (By similarity).
Contributes to the tryptophan-independent indole biosynthesis, and possibly to auxin production

Catalytic activity

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site58Proton acceptor
Active site69Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionindole-3-glycerol-phosphate lyase activity
Molecular Functiontryptophan synthase activity
Biological Processauxin biosynthetic process
Biological Processtryptophan metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tryptophan synthase alpha chain
  • EC number
  • Alternative names
    • Indole synthase
    • Indole-3-glycerol-phosphate lyase (EC:4.1.2.8) . EC:4.1.2.8 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      TRPA1
    • Synonyms
      INS, TSA
    • ORF names
      T10P11.11
    • Ordered locus names
      At4g02610

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    O22765
  • Secondary accessions
    • Q43290

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004206041-275Tryptophan synthase alpha chain

Proteomic databases

Expression

Tissue specificity

Ubiquitously expressed at low levels in seedlings, roots, hypocotyls, cotyledons, stems, leaves, inflorescences, flowers, siliques and seeds.

Developmental stage

Mostly present in vascular tissues. In flowers, expressed in carpels, stamens and pollen.

Gene expression databases

Interaction

Subunit

Tetramer of two alpha and two beta chains.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the TrpA family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    275
  • Mass (Da)
    29,579
  • Last updated
    1999-01-01 v2
  • Checksum
    BC1A027A1A53FA6A
MDLLKTPSSTVGLSETFARLKSQGKVALIPYITAGDPDLSTTAKALKVLDSCGSDIIELGVPYSDPLADGPAIQAAARRSLLKGTNFNSIISMLKEVIPQLSCPIALFTYYNPILRRGVENYMTVIKNAGVHGLLVPDVPLEETETLRNEARKHQIELVLLTTPTTPKERMNAIVEASEGFIYLVSSVGVTGTRESVNEKVQSLLQQIKEATSKPVAVGFGISKPEHVKQVAEWGADGVIVGSAMVKILGESESPEQGLKELEFFTKSLKSALVS

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict79-80in Ref. 5; CAA23378
Sequence conflict86-87in Ref. 5; CAA23378

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC002330
EMBL· GenBank· DDBJ
AAC78257.1
EMBL· GenBank· DDBJ
Genomic DNA
AL161494
EMBL· GenBank· DDBJ
CAB80754.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002687
EMBL· GenBank· DDBJ
AEE82204.1
EMBL· GenBank· DDBJ
Genomic DNA
AK117668
EMBL· GenBank· DDBJ
BAC42321.1
EMBL· GenBank· DDBJ
mRNA
BT006097
EMBL· GenBank· DDBJ
AAP04082.1
EMBL· GenBank· DDBJ
mRNA
F20005
EMBL· GenBank· DDBJ
CAA23378.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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