O22765 · TRPA1_ARATH
- ProteinTryptophan synthase alpha chain
- GeneTRPA1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids275 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate (By similarity).
Contributes to the tryptophan-independent indole biosynthesis, and possibly to auxin production
Contributes to the tryptophan-independent indole biosynthesis, and possibly to auxin production
Catalytic activity
- (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + L-tryptophan + H2O
Pathway
Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 58 | Proton acceptor | |||
Active site | 69 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | indole-3-glycerol-phosphate lyase activity | |
Molecular Function | tryptophan synthase activity | |
Biological Process | auxin biosynthetic process | |
Biological Process | tryptophan metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTryptophan synthase alpha chain
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionO22765
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000420604 | 1-275 | Tryptophan synthase alpha chain | ||
Proteomic databases
Expression
Tissue specificity
Ubiquitously expressed at low levels in seedlings, roots, hypocotyls, cotyledons, stems, leaves, inflorescences, flowers, siliques and seeds.
Developmental stage
Mostly present in vascular tissues. In flowers, expressed in carpels, stamens and pollen.
Gene expression databases
Interaction
Structure
Sequence
- Sequence statusComplete
- Length275
- Mass (Da)29,579
- Last updated1999-01-01 v2
- ChecksumBC1A027A1A53FA6A
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Sequence conflict | 79-80 | in Ref. 5; CAA23378 | |||
Sequence conflict | 86-87 | in Ref. 5; CAA23378 | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC002330 EMBL· GenBank· DDBJ | AAC78257.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AL161494 EMBL· GenBank· DDBJ | CAB80754.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002687 EMBL· GenBank· DDBJ | AEE82204.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AK117668 EMBL· GenBank· DDBJ | BAC42321.1 EMBL· GenBank· DDBJ | mRNA | ||
BT006097 EMBL· GenBank· DDBJ | AAP04082.1 EMBL· GenBank· DDBJ | mRNA | ||
F20005 EMBL· GenBank· DDBJ | CAA23378.1 EMBL· GenBank· DDBJ | mRNA |