O22396 · O22396_9CHLO

  • Protein
    Proliferating cell nuclear antigen
  • Gene
    PCNA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    2/5

Function

function

This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentPCNA complex
Molecular FunctionDNA binding
Molecular FunctionDNA polymerase processivity factor activity
Biological Processleading strand elongation
Biological Processmismatch repair
Biological Processregulation of DNA replication
Biological Processtranslesion synthesis

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Proliferating cell nuclear antigen

Gene names

    • Name
      PCNA

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • TA
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Chlorophyta > core chlorophytes > Chlorodendrophyceae > Chlorodendrales > Chlorodendraceae > Tetraselmis

Accessions

  • Primary accession
    O22396

Subcellular Location

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-70Proliferating cell nuclear antigen PCNA N-terminal
Domain73-200Proliferating cell nuclear antigen PCNA C-terminal

Sequence similarities

Belongs to the PCNA family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    205
  • Mass (Da)
    22,854
  • Last updated
    1998-01-01 v1
  • Checksum
    9FCF1609319ABF5E
EGFEHYRCDRSLSMGLNLGNMAKMLKCAGNDDVITIKADDKPDSLTFMMESPSQDRVSDFELKLMDIDSEHLGIPETEHQAVVKLPASEFQRICRDLSSIGDTVNISVTKDGVRFSTKGDIGSANISCRQNTSVDKPEEAVVIEMQEPVTLTFALRYLNSFAKATPLSSTVTLSMSKELPIVVEYRIQDMGFVKFYLAPKIEEDE

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue205

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF012212
EMBL· GenBank· DDBJ
AAB81177.2
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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