O21590 · NU3M_REIME

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular ComponentNADH dehydrogenase complex
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Biological Processmitochondrial electron transport, NADH to ubiquinone

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 3
  • EC number
  • Alternative names
    • NADH dehydrogenase subunit 3

Gene names

    • Name
      MT-ND3
    • Synonyms
      MTND3, NADH3, ND3

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Cricetidae > Neotominae > Reithrodontomys

Accessions

  • Primary accession
    O21590

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane4-24Helical
Transmembrane55-75Helical
Transmembrane87-107Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001178221-115NADH-ubiquinone oxidoreductase chain 3

Interaction

Subunit

Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits. Interacts with TMEM186. Interacts with TMEM242 (By similarity).

Structure

Family & Domains

Sequence similarities

Belongs to the complex I subunit 3 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    115
  • Mass (Da)
    13,114
  • Last updated
    1998-01-01 v1
  • Checksum
    8C71245A4A8189E0
MNMFIVLLVNISLASCLILIAFWLPQLNIYTEKANPYECGFDPMSSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAIQMSNIKATMLTSFILVSVLAMGLAYEWLQKGLEWTE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U83831
EMBL· GenBank· DDBJ
AAB87235.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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