O21325 · NU1M_DASNO

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex I
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Biological Processmitochondrial electron transport, NADH to ubiquinone
Biological Processmitochondrial respiratory chain complex I assembly

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 1
  • EC number
  • Alternative names
    • NADH dehydrogenase subunit 1

Gene names

    • Name
      MT-ND1
    • Synonyms
      MTND1, NADH1, ND1

Encoded on

  • Mitochondrion

Organism names

Accessions

  • Primary accession
    O21325

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane3-23Helical
Transmembrane69-89Helical
Transmembrane100-120Helical
Transmembrane135-155Helical
Transmembrane171-191Helical
Transmembrane223-243Helical
Transmembrane253-273Helical
Transmembrane293-313Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001173801-318NADH-ubiquinone oxidoreductase chain 1

Structure

Family & Domains

Sequence similarities

Belongs to the complex I subunit 1 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    318
  • Mass (Da)
    35,582
  • Last updated
    1998-01-01 v1
  • Checksum
    26E2DB45E712FF6A
MYLINVLSLIIPILLAVAFLTLLERKILGYMQLRKGPNIVGPYGLLQPIADAIKLFIKEPLRPATSSKLMFTLAPTLALTLALSLWIPIPMPYPLVNLNLGVLFILAMSSLAVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSIMMTNGSFTLSTLTTTQEHMWLIFPLWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFLAEYANIIMMNALTAILFFGAMHNPMFPELHTLNLITKTLILTMMFLWVRASYPRFRYDQLMHLLWKSFLPLTLALCMLHVSAPATFAGVPPHM

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Y11832
EMBL· GenBank· DDBJ
CAA72529.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp