O21280 · CCMA_RECAM

  • Protein
    Cytochrome c biogenesis ATP-binding export protein CcmA
  • Gene
    CCMA
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity).

Catalytic activity

Features

Showing features for binding site.

122220406080100120140160180200220
TypeIDPosition(s)Description
Binding site41-48ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial membrane
Molecular FunctionABC-type heme transporter activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Biological Processcytochrome complex assembly

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome c biogenesis ATP-binding export protein CcmA
  • EC number
  • Alternative names
    • Heme exporter protein A

Gene names

    • Name
      CCMA

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Strain
    • ATCC 50394
  • Taxonomic lineage
    Eukaryota > Discoba > Jakobida > Histionina > Histionidae > Reclinomonas

Accessions

  • Primary accession
    O21280

Subcellular Location

Mitochondrion membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000922291-222Cytochrome c biogenesis ATP-binding export protein CcmA

Interaction

Subunit

The complex is composed of two ATP-binding proteins (CcmA) and two transmembrane proteins (ccmB).

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain9-222ABC transporter

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    222
  • Mass (Da)
    25,502
  • Last updated
    1998-01-01 v1
  • Checksum
    A343CBFB8393A5A9
MNLTKIQNLTIHNITGIRSNKIIFQNINFSLEKGSLFIIQGSNGSGKTTLLKIISGLLPKSQGDIIINNNFISENYLKDSLFYMDSTPSFKEDITLLDYLIYWNTLYNGLQNISYEYIRTSLFQLGLSHLQNKKISTLSLGQKKRLLISKLLLTNKQLWILDEPLIGLDKYWIKIFSTILLKHCKRGGIIIMSTHTDLNIKKNTFLILNTTNKFIQTLNNLI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF007261
EMBL· GenBank· DDBJ
AAD11907.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp