O18645 · O18645_DROME

Function

Features

Showing features for binding site.

158250100150200250300350400450500550
TypeIDPosition(s)Description
Binding site57ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentbasolateral part of cell
Cellular Componentcytoplasm
Cellular Componentendosome
Cellular Componentnucleotide-activated protein kinase complex
Cellular Componentnucleus
Molecular FunctionAMP-activated protein kinase activity
Molecular FunctionATP binding
Molecular FunctionG protein-coupled receptor kinase activity
Molecular Functionprotein serine/threonine kinase activity
Biological Processbehavioral response to starvation
Biological Processcellular response to glucose starvation
Biological Processcellular response to starvation
Biological Processdendrite morphogenesis
Biological Processestablishment or maintenance of epithelial cell apical/basal polarity
Biological Processlipid metabolic process
Biological Processmitotic cell cycle
Biological Processnegative regulation of cell size
Biological Processnegative regulation of TOR signaling
Biological Processnegative regulation of TORC1 signaling
Biological Processpositive regulation of autophagosome assembly
Biological Processpositive regulation of axon guidance
Biological Processpositive regulation of cell population proliferation
Biological Processpositive regulation of lipophagy
Biological Processpositive regulation of macroautophagy
Biological Processpositive regulation of TORC1 signaling
Biological Processregulation of cell growth
Biological Processregulation of digestive system process
Biological Processsequestering of triglyceride

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    non-specific serine/threonine protein kinase
  • EC number

Gene names

    • Name
      AMPKalpha
    • Synonyms
      AK
      , AMPK
      , ampk
      , AMPK alpha
      , AMPK-alpha
      , AmpKalpha
      , ampkalpha
      , dAMPK
      , dAMPKa
      , dAMPKalpha
      , DmAMPK alpha
      , Dmel\CG3051
      , EG:132E8.2
      , FBgn0023169
      , Gprk-4
      , Gprk4
      , SNF1A
      , snf1A
      , snf1a
      , SNF1A-RA
      , SNF4A-a
    • ORF names
      CG3051
      , Dmel_CG3051

Organism names

  • Taxonomic identifier
  • Strains
    • Oregon-R
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    O18645
  • Secondary accessions
    • Q9U4G0

Proteomes

Organism-specific databases

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain28-280Protein kinase
Compositional bias387-408Polar residues
Region387-420Disordered

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    582
  • Mass (Da)
    64,600
  • Last updated
    1998-01-01 v1
  • Checksum
    8D68C4E3C8278BCB
MPQMRAAAAEAVAAGSANGQPLVKIGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWFQKDLPAYLFPSSIEQDSNVIDTYAVAEVCTKFGVKETEVHNSLLSGDPHDQLAIAYHLIIDNKRFADDAANQINEINNFFVAGSPPPPPPPPVPQSSMDHQAPLATVTVGGGTSASSGTATPVPPVAGGTPSSTIPIRPHPERIAPMRDRQLAMSVQTSGGGAFPEKTARGGTPIKRAKWHLGIRSQSKPNDIMLEVYRAMKALSYEWKIINPYHVRVRRQNVKTGKFSKMSLQLYQVDAKSYLLDFKSLTNDEVEQGDDVIMESLTPPPLSVSGVMPLQPTGHHTMEFFEMCAALIIQLAR

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias387-408Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF020309
EMBL· GenBank· DDBJ
AAB71397.1
EMBL· GenBank· DDBJ
Genomic DNA
AF020310
EMBL· GenBank· DDBJ
AAB71398.1
EMBL· GenBank· DDBJ
mRNA
AE014298
EMBL· GenBank· DDBJ
AAF45614.1
EMBL· GenBank· DDBJ
Genomic DNA
AE014298
EMBL· GenBank· DDBJ
AAN09043.1
EMBL· GenBank· DDBJ
Genomic DNA
AE014298
EMBL· GenBank· DDBJ
AAS65245.1
EMBL· GenBank· DDBJ
Genomic DNA
BT044168
EMBL· GenBank· DDBJ
ACH92233.1
EMBL· GenBank· DDBJ
mRNA
AL023893
EMBL· GenBank· DDBJ
CAA19653.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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