O17142 · O17142_DROME
- ProteinTranscriptional co-repressor SIN3A
- GeneSin3A
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1773 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | chromatin | |
Cellular Component | nucleus | |
Cellular Component | polytene chromosome | |
Cellular Component | Sin3-type complex | |
Cellular Component | transcription repressor complex | |
Molecular Function | chromatin binding | |
Molecular Function | protein heterodimerization activity | |
Molecular Function | transcription corepressor activity | |
Biological Process | determination of adult lifespan | |
Biological Process | epithelial cell migration | |
Biological Process | larval somatic muscle development | |
Biological Process | negative regulation of DNA-templated transcription | |
Biological Process | negative regulation of epithelial cell migration | |
Biological Process | negative regulation of transcription by RNA polymerase II | |
Biological Process | regulation of hemocyte proliferation | |
Biological Process | regulation of mitotic cell cycle | |
Biological Process | regulation of protein stability | |
Biological Process | wing disc development |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Protostomia > Ecdysozoa > Panarthropoda > Arthropoda (arthropods) > Mandibulata > Pancrustacea > Hexapoda (insects) > Insecta (true insects) > Dicondylia > Pterygota (winged insects) > Neoptera > Endopterygota > Diptera (flies) > Brachycera > Muscomorpha > Eremoneura > Cyclorrhapha > Schizophora > Acalyptratae > Ephydroidea > Drosophilidae (pomace flies) > Drosophilinae > Drosophilini > Drosophila (fruit flies) > Sophophora > melanogaster group > melanogaster subgroup
Accessions
- Primary accessionO17142
Organism-specific databases
Subcellular Location
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 186-207 | Disordered | ||||
Sequence: ANNPASAQTVSSSSQTGTIRQR | ||||||
Region | 231-267 | Disordered | ||||
Sequence: VQQSPLGKAQTPPSSVVANSIPVGGTTPPQGQSGNAT | ||||||
Region | 514-537 | Disordered | ||||
Sequence: PPTPNSLSELSPHGGAGGGPGAGA | ||||||
Region | 815-899 | Disordered | ||||
Sequence: PNQNLTHGHNAKKSPSYGIPSVIGSMPHISDNSLDRSSPGISYATPPLPSGPHGQHNSGSATRRPGDDSLVGHYASGAPPAKRPK | ||||||
Compositional bias | 840-858 | Polar residues | ||||
Sequence: MPHISDNSLDRSSPGISYA | ||||||
Region | 987-1015 | Disordered | ||||
Sequence: GLIDGMPLAATQRQGGGSSNSSHDRGTSH | ||||||
Compositional bias | 998-1015 | Polar residues | ||||
Sequence: QRQGGGSSNSSHDRGTSH | ||||||
Domain | 1029-1130 | Histone deacetylase interacting | ||||
Sequence: SCKRLGASYCALPQSTVPKKCSGRTALCREVLNDKWVSFPTWASEDSTFVTSRKTQFEETIYRTEDERFELDLVIEVNSATIRVLENLQKKMSRMSTEELSK | ||||||
Region | 1322-1459 | Disordered | ||||
Sequence: VDDNTKMDVDSPLGRTESSTRNAKSTPSESASPARSNASTSSVTPAGIKKETDDSKATTGSFAPASSATASSATPVDDATPSTSSAAAAASAASSSTVSGTEGKPKDDPLSSHKEEGAGCTSSGVATSPRQAQDTAGA | ||||||
Compositional bias | 1332-1369 | Polar residues | ||||
Sequence: SPLGRTESSTRNAKSTPSESASPARSNASTSSVTPAGI | ||||||
Compositional bias | 1378-1423 | Polar residues | ||||
Sequence: ATTGSFAPASSATASSATPVDDATPSTSSAAAAASAASSSTVSGTE | ||||||
Compositional bias | 1437-1455 | Polar residues | ||||
Sequence: EGAGCTSSGVATSPRQAQD | ||||||
Region | 1708-1749 | Disordered | ||||
Sequence: ALGGGGNTGRSDSALGNDSVVDGSDIKTEADEDTAEHTQSQQ |
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,773
- Mass (Da)190,090
- Last updated1998-01-01 v1
- ChecksumA72E9915D4B37456
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 840-858 | Polar residues | ||||
Sequence: MPHISDNSLDRSSPGISYA | ||||||
Compositional bias | 998-1015 | Polar residues | ||||
Sequence: QRQGGGSSNSSHDRGTSH | ||||||
Compositional bias | 1332-1369 | Polar residues | ||||
Sequence: SPLGRTESSTRNAKSTPSESASPARSNASTSSVTPAGI | ||||||
Compositional bias | 1378-1423 | Polar residues | ||||
Sequence: ATTGSFAPASSATASSATPVDDATPSTSSAAAAASAASSSTVSGTE | ||||||
Compositional bias | 1437-1455 | Polar residues | ||||
Sequence: EGAGCTSSGVATSPRQAQD |