O14683 · P5I11_HUMAN

  • Protein
    Tumor protein p53-inducible protein 11
  • Gene
    TP53I11
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Biological Processnegative regulation of cell population proliferation

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tumor protein p53-inducible protein 11
  • Alternative names
    • p53-induced gene 11 protein

Gene names

    • Name
      TP53I11
    • Synonyms
      PIG11

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    O14683
  • Secondary accessions
    • Q3ZCS0

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-63Cytoplasmic
Transmembrane64-84Helical
Topological domain85-108Extracellular
Transmembrane109-129Helical
Topological domain130Cytoplasmic
Transmembrane131-151Helical
Topological domain152-155Extracellular
Transmembrane156-176Helical
Topological domain177-189Cytoplasmic

Keywords

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 206 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Organism-specific databases

Miscellaneous

Genetic variation databases

PTM/Processing

Features

Showing features for chain, modified residue, modified residue (large scale data).

TypeIDPosition(s)SourceDescription
ChainPRO_00000581421-189UniProtTumor protein p53-inducible protein 11
Modified residue14UniProtPhosphoserine
Modified residue (large scale data)14PRIDEPhosphoserine
Modified residue (large scale data)16PRIDEPhosphothreonine
Modified residue (large scale data)20PRIDEPhosphoserine

Keywords

Proteomic databases

PTM databases

Expression

Induction

By p53/TP53.

Gene expression databases

Organism-specific databases

Interaction

Protein-protein interaction databases

Miscellaneous

Family & Domains

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    189
  • Mass (Da)
    21,054
  • Last updated
    2010-06-15 v2
  • Checksum
    5E858F5872FE3171
MAAKQPPPLMKKHSQTDLVSRLKTRKILGVGGEDDDGEVHRSKISQVLGNEIKFTIREPLGLRVWQFVSAVLFSGIAIMALAFPDQLYDAVFDGAQVTSKTPIRLYGGALLSISLIMWNALYTAEKVIIRWTLLTEACYFGVQFLVVTATLAETGLMSLGILLLLVSRLLFVVISIYYYYQVGRRPKKA

Computationally mapped potential isoform sequences

There are 12 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
E9PS55E9PS55_HUMANTP53I1179
E9PPM1E9PPM1_HUMANTP53I11236
E9PQ46E9PQ46_HUMANTP53I1198
E9PNB3E9PNB3_HUMANTP53I1164
E9PMW4E9PMW4_HUMANTP53I1193
E9PMY0E9PMY0_HUMANTP53I1191
E9PKZ4E9PKZ4_HUMANTP53I11158
E9PN66E9PN66_HUMANTP53I1162
E9PKN9E9PKN9_HUMANTP53I1173
E9PIK4E9PIK4_HUMANTP53I11126
E9PIN5E9PIN5_HUMANTP53I11123
U3KQ32U3KQ32_HUMANTP53I11154

Sequence caution

The sequence AAC39533.1 differs from that shown. Reason: Miscellaneous discrepancy Localized in an untranslated region: wrong choice of CDS.

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF010315
EMBL· GenBank· DDBJ
AAC39533.1
EMBL· GenBank· DDBJ
mRNA Sequence problems.
AK292837
EMBL· GenBank· DDBJ
BAF85526.1
EMBL· GenBank· DDBJ
mRNA
AC068858
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC092733
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CH471064
EMBL· GenBank· DDBJ
EAW68052.1
EMBL· GenBank· DDBJ
Genomic DNA
CH471064
EMBL· GenBank· DDBJ
EAW68053.1
EMBL· GenBank· DDBJ
Genomic DNA
CH471064
EMBL· GenBank· DDBJ
EAW68055.1
EMBL· GenBank· DDBJ
Genomic DNA
CH471064
EMBL· GenBank· DDBJ
EAW68057.1
EMBL· GenBank· DDBJ
Genomic DNA
BC045666
EMBL· GenBank· DDBJ
AAH45666.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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