O14683 · P5I11_HUMAN
- ProteinTumor protein p53-inducible protein 11
- GeneTP53I11
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids189 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Biological Process | negative regulation of cell population proliferation |
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTumor protein p53-inducible protein 11
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionO14683
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-63 | Cytoplasmic | ||||
Sequence: MAAKQPPPLMKKHSQTDLVSRLKTRKILGVGGEDDDGEVHRSKISQVLGNEIKFTIREPLGLR | ||||||
Transmembrane | 64-84 | Helical | ||||
Sequence: VWQFVSAVLFSGIAIMALAFP | ||||||
Topological domain | 85-108 | Extracellular | ||||
Sequence: DQLYDAVFDGAQVTSKTPIRLYGG | ||||||
Transmembrane | 109-129 | Helical | ||||
Sequence: ALLSISLIMWNALYTAEKVII | ||||||
Topological domain | 130 | Cytoplasmic | ||||
Sequence: R | ||||||
Transmembrane | 131-151 | Helical | ||||
Sequence: WTLLTEACYFGVQFLVVTATL | ||||||
Topological domain | 152-155 | Extracellular | ||||
Sequence: AETG | ||||||
Transmembrane | 156-176 | Helical | ||||
Sequence: LMSLGILLLLVSRLLFVVISI | ||||||
Topological domain | 177-189 | Cytoplasmic | ||||
Sequence: YYYYQVGRRPKKA |
Keywords
- Cellular component
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 206 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Miscellaneous
Genetic variation databases
PTM/Processing
Features
Showing features for chain, modified residue, modified residue (large scale data).
Type | ID | Position(s) | Source | Description | |||
---|---|---|---|---|---|---|---|
Chain | PRO_0000058142 | 1-189 | UniProt | Tumor protein p53-inducible protein 11 | |||
Sequence: MAAKQPPPLMKKHSQTDLVSRLKTRKILGVGGEDDDGEVHRSKISQVLGNEIKFTIREPLGLRVWQFVSAVLFSGIAIMALAFPDQLYDAVFDGAQVTSKTPIRLYGGALLSISLIMWNALYTAEKVIIRWTLLTEACYFGVQFLVVTATLAETGLMSLGILLLLVSRLLFVVISIYYYYQVGRRPKKA | |||||||
Modified residue | 14 | UniProt | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 14 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 16 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 20 | PRIDE | Phosphoserine | ||||
Sequence: S |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Structure
Sequence
- Sequence statusComplete
- Length189
- Mass (Da)21,054
- Last updated2010-06-15 v2
- Checksum5E858F5872FE3171
Computationally mapped potential isoform sequences
There are 12 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
E9PS55 | E9PS55_HUMAN | TP53I11 | 79 | ||
E9PPM1 | E9PPM1_HUMAN | TP53I11 | 236 | ||
E9PQ46 | E9PQ46_HUMAN | TP53I11 | 98 | ||
E9PNB3 | E9PNB3_HUMAN | TP53I11 | 64 | ||
E9PMW4 | E9PMW4_HUMAN | TP53I11 | 93 | ||
E9PMY0 | E9PMY0_HUMAN | TP53I11 | 91 | ||
E9PKZ4 | E9PKZ4_HUMAN | TP53I11 | 158 | ||
E9PN66 | E9PN66_HUMAN | TP53I11 | 62 | ||
E9PKN9 | E9PKN9_HUMAN | TP53I11 | 73 | ||
E9PIK4 | E9PIK4_HUMAN | TP53I11 | 126 | ||
E9PIN5 | E9PIN5_HUMAN | TP53I11 | 123 | ||
U3KQ32 | U3KQ32_HUMAN | TP53I11 | 154 |
Sequence caution
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF010315 EMBL· GenBank· DDBJ | AAC39533.1 EMBL· GenBank· DDBJ | mRNA | Sequence problems. | |
AK292837 EMBL· GenBank· DDBJ | BAF85526.1 EMBL· GenBank· DDBJ | mRNA | ||
AC068858 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC092733 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CH471064 EMBL· GenBank· DDBJ | EAW68052.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CH471064 EMBL· GenBank· DDBJ | EAW68053.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CH471064 EMBL· GenBank· DDBJ | EAW68055.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CH471064 EMBL· GenBank· DDBJ | EAW68057.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BC045666 EMBL· GenBank· DDBJ | AAH45666.1 EMBL· GenBank· DDBJ | mRNA |