The mouse homolog of PKD1: sequence analysis and alternative splicing.Lohning C., Nowicka U., Frischauf A.M.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMamm. Genome 8:307-311 (1997)Cited in1Mapped to11
Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells.Nauli S.M., Alenghat F.J., Luo Y., Williams E., Vassilev P., Li X., Elia A.E., Lu W., Brown E.M.[...], Zhou J.View abstractCited forFUNCTION, SUBCELLULAR LOCATIONCategoriesFunction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Genet. 33:129-137 (2003)Cited in2Mapped to16
Genomic organization and functional analysis of murine PKD2L1.Murakami M., Ohba T., Xu F., Shida S., Satoh E., Ono K., Miyoshi I., Watanabe H., Ito H., Iijima T.View abstractCited forINTERACTION WITH PKD2L1CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 280:5626-5635 (2005)Cited in2Mapped to11
Essential role of cleavage of Polycystin-1 at G protein-coupled receptor proteolytic site for kidney tubular structure.Yu S., Hackmann K., Gao J., He X., Piontek K., Garcia-Gonzalez M.A., Menezes L.F., Xu H., Germino G.G.[...], Qian F.View abstractCited forDISRUPTION PHENOTYPE, DIFFERENTIAL PATTERN OF AUTOCLEAVAGECategoriesPTM / Processing, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 104:18688-18693 (2007)Cited in1Mapped to22
Identification of signaling pathways regulating primary cilium length and flow-mediated adaptation.Besschetnova T.Y., Kolpakova-Hart E., Guan Y., Zhou J., Olsen B.R., Shah J.V.View abstractCited forFUNCTION AS REGULATOR OF CILIUM LENGTHCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCurr. Biol. 20:182-187 (2010)Cited in2
Nephrocystin-1 forms a complex with polycystin-1 via a polyproline motif/SH3 domain interaction and regulates the apoptotic response in mammals.Wodarczyk C., Distefano G., Rowe I., Gaetani M., Bricoli B., Muorah M., Spitaleri A., Mannella V., Ricchiuto P.[...], Boletta A.View abstractCited forINTERACTION WITH NPHP1CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCPLoS ONE 5:E12719-E12719 (2010)Cited in4Mapped to34
Bardet-Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 protein.Su X., Driscoll K., Yao G., Raed A., Wu M., Beales P.L., Zhou J.View abstractCited forFUNCTION, SUBCELLULAR LOCATIONCategoriesFunction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCHum. Mol. Genet. 23:5441-5451 (2014)Cited in7Mapped to39
Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism.Kim H., Xu H., Yao Q., Li W., Huang Q., Outeda P., Cebotaru V., Chiaravalli M., Boletta A.[...], Qian F.View abstractCited forSUBCELLULAR LOCATION, INTERACTION WITH PKD2 AND RABEP1, AUTOCATALYTIC CLEAVAGECategoriesPTM / Processing, Interaction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Commun. 5:5482-5482 (2014)Cited in5Mapped to19
The polycystin complex mediates Wnt/Ca(2+) signalling.Kim S., Nie H., Nesin V., Tran U., Outeda P., Bai C.X., Keeling J., Maskey D., Watnick T.[...], Tsiokas L.View abstractCited forINTERACTION WITH WNT5A; DVL1 AND DVL2CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Cell Biol. 18:752-764 (2016)Cited in13
The gene encoding ribosomal protein S19 is mutated in Diamond-Blackfan anaemia.Draptchinskaia N., Gustavsson P., Andersson B., Pettersson M., Willig T.-N.D., Dianzani I., Ball S., Tchernia G., Klar J.[...], Dahl N.View abstractCategoriesSequencesSourceMGI: 97603PubMedEurope PMCNat. Genet. 21:169-175 (1999)Cited in1Mapped to19
Late onset of renal and hepatic cysts in Pkd1-targeted heterozygotes.Lu W., Fan X., Basora N., Babakhanlou H., Law T., Rifai N., Harris P.C., Perez-Atayde A.R., Rennke H.G., Zhou J.CategoriesPhenotypes & VariantsSourceMGI: 97603PubMedEurope PMCNat Genet 21:160-161 (1999)Mapped to12
Murine Pkd1 introns 21 and 22 lack the extreme polypyrimidine bias present in human PKD1.Piontek K.B., Germino G.G.CategoriesFunction, SequencesSourceMGI: 97603PubMedEurope PMCMamm Genome 10:194-196 (1999)Mapped to12
Somatic inactivation of Pkd2 results in polycystic kidney disease.Wu G., D'Agati V., Cai Y., Markowitz G., Park J.H., Reynolds D.M., Maeda Y., Le T.C., Hou H. Jr.[...], Somlo S.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 97603PubMedEurope PMCCell 93:177-188 (1998)Cited in1Mapped to12
Expression of polycystin in mouse metanephros and extra-metanephric tissues.Griffin M.D., O'Sullivan D.A., Torres V.E., Grande J.P., Kanwar Y.S., Kumar R.View abstractCategoriesSequences, ExpressionSourceMGI: 97603PubMedEurope PMCKidney Int 52:1196-1205 (1997)Mapped to12
Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation.Lu W., Peissel B., Babakhanlou H., Pavlova A., Geng L., Fan X., Larson C., Brent G., Zhou J.View abstractCategoriesPhenotypes & VariantsSourceMGI: 97603PubMedEurope PMCNat Genet 17:179-181 (1997)Mapped to12
Cystic kidney diseases.Griffin M.D., Torres V.E., Kumar R.View abstractCategoriesNamesSourceMGI: 97603PubMedEurope PMCCurr Opin Nephrol Hypertens 6:276-283 (1997)Mapped to23
Distribution and developmentally regulated expression of murine polycystin.Geng L., Segal Y., Pavlova A., Barros E.J., Lohning C., Lu W., Nigam S.K., Frischauf A.M., Reeders S.T., Zhou J.View abstractCategoriesSequencesSourceMGI: 97603PubMedEurope PMCAm J Physiol 272:F451-9 (1997)Mapped to12
Generation of a transcriptional map for a 700-kb region surrounding the polycystic kidney disease type 1 (PKD1) and tuberous sclerosis type 2 (TSC2) disease genes on human chromosome 16p3.3.Burn T.C., Connors T.D., Van Raay T.J., Dackowski W.R., Millholland J.M., Klinger K.W., Landes G.M.View abstractCategoriesSequencesSourceMGI: 97603PubMedEurope PMCGenome Res. 6:525-537 (1996)Cited in1Mapped to28
Advances in polycystic kidney disease.Schneider M.C.View abstractCategoriesSequencesSourceMGI: 97603PubMedEurope PMCMol Med Today 2:70-75 (1996)Mapped to12
The mouse homologue of the polycystic kidney disease gene (Pkd1) is a single-copy gene.Olsson P.G., Lohning C., Horsley S., Kearney L., Harris P.C., Frischauf A.View abstractCategoriesSequencesSourceMGI: 97603PubMedEurope PMCGenomics 34:233-235 (1996)Mapped to28
Animal models of polycystic kidney disease.Aziz N.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 97603PubMedEurope PMCBioessays 17:703-712 (1995)Mapped to30
Reduced decay-accelerating factor expression promotes complement-mediated cystogenesis in murine ADPKD.Bin S., Yoo M., Molinari P., Gentile M., Budge K., Cantarelli C., Khan Y., La Manna G., Baldwin W.M.[...], Gusella G.L.View abstractAnnotationReduced decay-accelerating factor expression promotes complement-mediated cystogenesis in murine ADPKD.SourceGeneRif: 18763PubMedEurope PMCJCI Insight 9:e175220-e175220 (2024)Mapped to6
Calcium signaling induces partial EMT and renal fibrosis in a Wnt4<sup>mCherry</sup> knock-in mouse model.Naillat F., Deshar G., Hankkila A., Rak-Raszewska A., Sharma A., Prunskaite-Hyyrylainen R., Railo A., Shan J., Vainio S.J.View abstractSourceMGI: 97603PubMedEurope PMCBiochim Biophys Acta Mol Basis Dis 1870:167180-167180 (2024)Mapped to99+
Mechanosensitive protein polycystin-1 promotes periosteal stem/progenitor cells osteochondral differentiation in fracture healing.Liu R., Jiao Y.R., Huang M., Zou N.Y., He C., Huang M., Chen K.X., He W.Z., Liu L.[...], Li C.J.View abstractAnnotationMechanosensitive protein polycystin-1 promotes periosteal stem/progenitor cells osteochondral differentiation in fracture healing.SourceGeneRif: 18763PubMedEurope PMCTheranostics 14:2544-2559 (2024)Mapped to6