O04291 · ATB14_ARATH

Function

function

Probable transcription factor involved in the determination of adaxial-abaxial polarity in ovule primordium. Specifies adaxial leaf fates.

Activity regulation

Inhibited by ZPR3.

Features

Showing features for dna binding.

1852100200300400500600700800
TypeIDPosition(s)Description
DNA binding22-85Homeobox

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA binding
Molecular FunctionDNA-binding transcription factor activity
Molecular Functionlipid binding
Biological Processadaxial/abaxial pattern specification
Biological Processcell differentiation
Biological Processdetermination of bilateral symmetry
Biological Processintegument development
Biological Processmeristem initiation
Biological Processpolarity specification of adaxial/abaxial axis
Biological Processprimary shoot apical meristem specification

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Homeobox-leucine zipper protein ATHB-14
  • Alternative names
    • HD-ZIP protein ATHB-14
    • Homeodomain transcription factor ATHB-14
    • Protein PHABULOSA

Gene names

    • Name
      ATHB-14
    • Synonyms
      PHB
    • ORF names
      T29F13.8
    • Ordered locus names
      At2g34710

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    O04291

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

Phenotypes & Variants

Features

Showing features for mutagenesis.

TypeIDPosition(s)Description
Mutagenesis202In phb-3d, phb-4d and phb-5d; constitutively active. Transformation of abaxial leaf fates into adaxial leaf fates.

Variants

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The viewer provides 60 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003316601-852Homeobox-leucine zipper protein ATHB-14

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in the center of the meristem and on the adaxial side of the leaves.

Induction

Repressed by miR165 and miR166.

Developmental stage

Expressed at the youngest stages of ovule development, predominantly to the adaxial side of the ovule primordium. Later, expression becomes restricted to a region in the distal chalaza. When the integuments initiate, expressed in the inner integument, with highest expression in the inner layer of the inner integument. Expressed in the vegetative shoot apical meristem (SAM) and initially throughout the presumptive cotyledons. At the globular stage, just before cotyledon outgrowth, expressed at high levels in cotyledon adaxial domains. Expression is lost from the SAM of torpedo stage embryos but is regained late in embryogenesis, extending to young primordia after germination, and becoming progressively restricted to the adaxial domain and the vasculature. Preferentially expressed in the adaxial domain of the developing leaf. Expressed throughout the plastochron 0 (P0) leaf primordium and expression increases in P1 to become preferentially localized to the adaxial leaf domain by the P2 stage (polar expression).

Gene expression databases

Interaction

Subunit

Homodimer (PubMed:18408069).
Heterodimer with ZPR3 (PubMed:18408069).
Interacts with ESR1 and ESR2 (PubMed:17376809).
Interacts with ZPR3 (PubMed:18408069).

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, coiled coil, domain.

TypeIDPosition(s)Description
Region1-25Disordered
Coiled coil80-122
Region80-130ZIP domain
Region130-166Disordered
Domain164-392START

Domain

The ZIP domain (80-130) is necessary and sufficient for the interaction with ZPR3 (PubMed:18408069).

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    852
  • Mass (Da)
    93,218
  • Last updated
    1997-07-01 v1
  • Checksum
    C1802529EFCC4E68
MMMVHSMSRDMMNRESPDKGLDSGKYVRYTPEQVEALERVYTECPKPSSLRRQQLIRECPILSNIEPKQIKVWFQNRRCREKQRKEAARLQTVNRKLNAMNKLLMEENDRLQKQVSNLVYENGHMKHQLHTASGTTTDNSCESVVVSGQQHQQQNPNPQHQQRDANNPAGLLSIAEEALAEFLSKATGTAVDWVQMIGMKPGPDSIGIVAISRNCSGIAARACGLVSLEPMKVAEILKDRPSWLRDCRSVDTLSVIPAGNGGTIELIYTQMYAPTTLAAARDFWTLRYSTCLEDGSYVVCERSLTSATGGPTGPPSSNFVRAEMKPSGFLIRPCDGGGSILHIVDHVDLDAWSVPEVMRPLYESSKILAQKMTVAALRHVRQIAQETSGEVQYGGGRQPAVLRTFSQRLCRGFNDAVNGFVDDGWSPMGSDGAEDVTVMINLSPGKFGGSQYGNSFLPSFGSGVLCAKASMLLQNVPPAVLVRFLREHRSEWADYGVDAYAAASLRASPFAVPCARAGGFPSNQVILPLAQTVEHEESLEVVRLEGHAYSPEDMGLARDMYLLQLCSGVDENVVGGCAQLVFAPIDESFADDAPLLPSGFRIIPLEQKSTPNGASANRTLDLASALEGSTRQAGEADPNGCNFRSVLTIAFQFTFDNHSRDSVASMARQYVRSIVGSIQRVALAIAPRPGSNISPISVPTSPEALTLVRWISRSYSLHTGADLFGSDSQTSGDTLLHQLWNHSDAILCCSLKTNASPVFTFANQTGLDMLETTLVALQDIMLDKTLDEPGRKALCSEFPKIMQQGYAHLPAGVCASSMGRMVSYEQATVWKVLEDDESNHCLAFMFVNWSFV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Y11122
EMBL· GenBank· DDBJ
CAA72007.1
EMBL· GenBank· DDBJ
Genomic DNA
AJ441291
EMBL· GenBank· DDBJ
CAD29659.1
EMBL· GenBank· DDBJ
mRNA
AC003096
EMBL· GenBank· DDBJ
AAC16263.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC09012.1
EMBL· GenBank· DDBJ
Genomic DNA
AY099791
EMBL· GenBank· DDBJ
AAM20642.1
EMBL· GenBank· DDBJ
mRNA
BT000335
EMBL· GenBank· DDBJ
AAN15654.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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