O04274 · LDOX_PERFR

Function

function

Oxidation of leucoanthocyanidins into anthocyanidins.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Fe cation (UniProtKB | Rhea| CHEBI:24875 )

Note: Binds 1 Fe cation per subunit.
L-ascorbate (UniProtKB | Rhea| CHEBI:38290 )

Note: Binds 1 ascorbate molecule per subunit.

Pathway

Pigment biosynthesis; anthocyanin biosynthesis.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site238Fe cation (UniProtKB | ChEBI)
Binding site240Fe cation (UniProtKB | ChEBI)
Binding site294Fe cation (UniProtKB | ChEBI)
Active site304

GO annotations

AspectTerm
Molecular FunctionL-ascorbic acid binding
Molecular Functionleucocyanidin oxygenase activity
Molecular Functionmetal ion binding
Biological Processanthocyanin-containing compound biosynthetic process
Biological Processcoumarin biosynthetic process
Biological Processresponse to molecule of fungal origin

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Leucoanthocyanidin dioxygenase
  • EC number
  • Short names
    LDOX; Leucocyanidin oxygenase
  • Alternative names
    • Leucoanthocyanidin hydroxylase

Gene names

    • Name
      ANS

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > lamiids > Lamiales > Lamiaceae > Nepetoideae > Elsholtzieae > Perilla

Accessions

  • Primary accession
    O04274

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000673021-362Leucoanthocyanidin dioxygenase

Expression

Tissue specificity

Expressed in red but not in green forma of P.frutescens. In red forma, it is predominantly expressed in stems and leaves, but not in roots.

Structure

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region1-23Disordered
Domain214-313Fe2OG dioxygenase

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    362
  • Mass (Da)
    40,826
  • Last updated
    1997-07-01 v1
  • Checksum
    7A03B4E86F91E1EA
MVTSAMGPSPRVEELARSGLDTIPKDYVRPEEELKSIIGNILAEEKSSEGPQLPTIDLEEMDSRDEEGRKKCHEELKKAATDWGVMHLINHGIPEELIDRVKAAGKEFFELPVEEKEAYANDQAAGNVQGYGSKLANNASGQLEWEDYFFHCVYPEHKTDLSIWPTKPPDYIPATSEYAKQLRALATKILSVLSIGLGLEKGRLEKEVGGAEDLIVQMKINFYPKCPQPELALGWEAHTDVSALTFILHNMVPGLQLFYEDKWVTAKCVPNSIIMHIGDTLEILSNGKYKSILHRGLVNKEKVRISWAVFCEPPKEKIVLQPLPETVSEVEPPRFPPRTFAQHLKHKLFRKTDGDLDEKPTY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB003779
EMBL· GenBank· DDBJ
BAA20143.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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