O03376 · AOX3_SOYBN

Function

function

Catalyzes the cyanide-resistant oxidation of ubiquinol and the reduction of molecular oxygen to water, but does not translocate protons and consequently is not linked to oxidative phosphorylation. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures (By similarity).

Catalytic activity

Cofactor

Fe cation (UniProtKB | Rhea| CHEBI:24875 )

Note: Binds 2 iron ions per subunit.

Features

Showing features for binding site.

132650100150200250300
TypeIDPosition(s)Description
Binding site155Fe cation 1 (UniProtKB | ChEBI)
Binding site194Fe cation 1 (UniProtKB | ChEBI)
Binding site194Fe cation 2 (UniProtKB | ChEBI)
Binding site197Fe cation 1 (UniProtKB | ChEBI)
Binding site245Fe cation 2 (UniProtKB | ChEBI)
Binding site296Fe cation 1 (UniProtKB | ChEBI)
Binding site296Fe cation 2 (UniProtKB | ChEBI)
Binding site299Fe cation 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentmitochondrion
Molecular Functionalternative oxidase activity
Molecular Functionmetal ion binding
Molecular Functionsuperoxide-generating NADPH oxidase activity
Molecular Functionubiquinol:oxygen oxidoreductase activity
Biological Processalternative respiration

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Alternative oxidase 3, mitochondrial
  • EC number

Gene names

    • Name
      AOX3

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Fabales > Fabaceae > Papilionoideae > 50 kb inversion clade > NPAAA clade > indigoferoid/millettioid clade > Phaseoleae > Glycine > Glycine subgen. Soja

Accessions

  • Primary accession
    O03376

Proteomes

Subcellular Location

Mitochondrion inner membrane
; Multi-pass membrane protein
Note: Mitochondrial, possibly in the inner surface of the inner mitochondrial membrane.

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane151-171Helical
Transmembrane213-233Helical

Keywords

Phenotypes & Variants

Features

Showing features for mutagenesis.

TypeIDPosition(s)Description
Mutagenesis99Loss of oxidative inactivation and stimulation by pyruvate, but can be activated by succinate.

PTM/Processing

Features

Showing features for chain, transit peptide, disulfide bond.

Type
IDPosition(s)Description
ChainPRO_0000001739?-326Alternative oxidase 3, mitochondrial
Transit peptide1-?Mitochondrion
Disulfide bond99Interchain

Keywords

Proteomic databases

Expression

Developmental stage

Continuous increase of expression in developing cotyledons until day 20.

Interaction

Subunit

Homodimer; disulfide-linked.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the alternative oxidase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    326
  • Mass (Da)
    37,057
  • Last updated
    1997-07-01 v1
  • Checksum
    8F1CB9EBCBD58A0E
MKNVLVRSAARALLGGGGRSYYRQLSTAAIVEQRHQHGGGAFGSFHLRRMSTLPEVKDQHSEEKKNEVNGTSNAVVTSYWGITRPKVRREDGTEWPWNCFMPWDSYHSDVSIDVTKHHTPKSLTDKVAFRAVKFLRVLSDIYFKERYGCHAMMLETIAAVPGMVGGMLLHLKSLRKFQHSGGWIKALLEEAENERMHLMTMVELVKPSWHERLLIFTAQGVFFNAFFVFYLLSPKAAHRFVGYLEEEAVISYTQHLNAIESGKVENVPAPAIAIDYWRLPKDATLKDVVTVIRADEAHHRDVNHFASDIHHQGKELKEAPAPIGYH

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U87907
EMBL· GenBank· DDBJ
AAB97286.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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