O03376 · AOX3_SOYBN
- ProteinAlternative oxidase 3, mitochondrial
- GeneAOX3
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids326 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Catalyzes the cyanide-resistant oxidation of ubiquinol and the reduction of molecular oxygen to water, but does not translocate protons and consequently is not linked to oxidative phosphorylation. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures (By similarity).
Catalytic activity
- 2 a ubiquinol + O2 = 2 a ubiquinone + 2 H2O
Cofactor
Note: Binds 2 iron ions per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 155 | Fe cation 1 (UniProtKB | ChEBI) | |||
Binding site | 194 | Fe cation 1 (UniProtKB | ChEBI) | |||
Binding site | 194 | Fe cation 2 (UniProtKB | ChEBI) | |||
Binding site | 197 | Fe cation 1 (UniProtKB | ChEBI) | |||
Binding site | 245 | Fe cation 2 (UniProtKB | ChEBI) | |||
Binding site | 296 | Fe cation 1 (UniProtKB | ChEBI) | |||
Binding site | 296 | Fe cation 2 (UniProtKB | ChEBI) | |||
Binding site | 299 | Fe cation 2 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Cellular Component | mitochondrion | |
Molecular Function | alternative oxidase activity | |
Molecular Function | metal ion binding | |
Molecular Function | superoxide-generating NADPH oxidase activity | |
Molecular Function | ubiquinol:oxygen oxidoreductase activity | |
Biological Process | alternative respiration |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAlternative oxidase 3, mitochondrial
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Fabales > Fabaceae > Papilionoideae > 50 kb inversion clade > NPAAA clade > indigoferoid/millettioid clade > Phaseoleae > Glycine > Glycine subgen. Soja
Accessions
- Primary accessionO03376
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Multi-pass membrane protein
Note: Mitochondrial, possibly in the inner surface of the inner mitochondrial membrane.
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 151-171 | Helical | |||
Transmembrane | 213-233 | Helical | |||
Keywords
- Cellular component
Phenotypes & Variants
Features
Showing features for mutagenesis.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Mutagenesis | 99 | Loss of oxidative inactivation and stimulation by pyruvate, but can be activated by succinate. | |||
PTM/Processing
Features
Showing features for chain, transit peptide, disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000001739 | ?-326 | Alternative oxidase 3, mitochondrial | ||
Transit peptide | 1-? | Mitochondrion | |||
Disulfide bond | 99 | Interchain | |||
Keywords
- PTM
Proteomic databases
Expression
Developmental stage
Continuous increase of expression in developing cotyledons until day 20.
Interaction
Structure
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length326
- Mass (Da)37,057
- Last updated1997-07-01 v1
- Checksum8F1CB9EBCBD58A0E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
U87907 EMBL· GenBank· DDBJ | AAB97286.1 EMBL· GenBank· DDBJ | mRNA |