O03288 · O03288_STEPR

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

134050100150200250300
TypeIDPosition(s)Description
Binding site50Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site64Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site149Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site163Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site168a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      cytb

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Strain
    • Bird J313
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Charadriiformes > Stercorariidae > Stercorarius

Accessions

  • Primary accession
    O03288

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane53-72Helical
Transmembrane84-106Helical
Transmembrane145-166Helical
Transmembrane187-212Helical
Transmembrane255-275Helical
Transmembrane287-307Helical
Transmembrane313-336Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-19
ChainPRO_500415685320-340Cytochrome b

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-176Cytochrome b/b6 N-terminal region profile
Domain177-340Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    340
  • Mass (Da)
    38,047
  • Last updated
    1997-07-01 v1
  • Checksum
    CD6EC27CBAF34CEF
GSLLGICLLTQILTGLLLAMHYTADTTLAFTSVAHTCRNVQYGWLIRNLHANGASFFFICIYLHIGRGFYYGSYLYQETWNTGVILLLTLMATAFVGXXXXXXXXXXXXXXXXXNLFSAIPYIGQTLVEWAWGGFSVDSPTLTRFFALHFLLPFVIAGLTLIHLTFLHESGSNNPLXIVSNCDKIPFHPYFSLXDILGFIIMLFPLMTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLVLFLTPLLHKSKQRTMTFRPLSQLLFWTLVANLFILTWVGSQPVEHPFIIIGQLASFTYFATLLFLFPIIGTLE

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue340

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U76829
EMBL· GenBank· DDBJ
AAC60201.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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