N6TZK4 · N6TZK4_DENPD

Function

Catalytic activity

Features

Showing features for binding site.

1764100200300400500600700
TypeIDPosition(s)Description
Binding site43ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcentriole
Cellular Componentcentrosome
Cellular Componentcytoplasm
Cellular Componentkinetochore
Cellular Componentnucleus
Cellular Componentspindle pole
Molecular FunctionATP binding
Molecular Functionprotein serine/threonine kinase activity
Biological Processmitotic spindle organization
Biological Processprotein phosphorylation
Biological Processregulation of cell cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Serine/threonine-protein kinase PLK4
  • EC number
  • Alternative names
    • Polo-like kinase 4
    • Serine/threonine-protein kinase SAK

Gene names

    • Name
      109541525
    • ORF names
      YQE_09574

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Coleoptera > Polyphaga > Cucujiformia > Curculionidae > Scolytinae > Dendroctonus

Accessions

  • Primary accession
    N6TZK4

Proteomes

Subcellular Location

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain14-265Protein kinase
Region338-377Disordered
Compositional bias348-363Polar residues
Domain430-547Cryptic POLO box 1 (CPB1)
Domain548-655Cryptic POLO box 2 (CPB2)
Domain675-753POLO box

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    764
  • Mass (Da)
    85,336
  • Last updated
    2013-06-26 v1
  • Checksum
    96C01C6E97945DAB
MNSRYSFSDKIEDYEVHELLGKGGFASVYRAMCRKTGIDVAIKMIDKKLMQAEGMVGRVQQEVSIHSRLKHPSILELYTFFEDANYVYLILELCHNGELQQYTKRKRLIESQVSNVMKQVVEGIKYLHFHSILHRDISLSNLLLTKDMQVKIADFGLATQLSRPDEKHRTMCGTPNFISPEVATRGSHGLEVDVWGLGCLLYTLLVGLPPFETNGVKSTLTRVVMASYSLPSHLSPEAKDLINSLLQKNPKDRIGLEQILEHPFIKRNIVLSTNLTQDSGIHTMSSRRDSAFSDGALPSSYSSNMLHFRKASSDCFPCEPNLMPSNRQTHSMEYAHHQPPHFSRDQYQDVPASPSQYSNNCYHPNDPGGGGLSGHSASQILAGIPTKTTPLLSQCSNSLGNRLENMCLSQETSLALPRYHSGNKPMGGVEKSQTLIQLCSHRLLPTRHQTKNAILSIQDDGEVTVEFIKKKGSLKRELVCEIMRISPDGLRIVMYEPEGGRGATPSSEPAPLPEQGADRIYSIENLPEKHWKKYMYAFKFVELVRAKTPKVTFYSDKAKCLLMENLVDFEVCFYEGGKVTRSTTEGVSLVEPSGLKYSFPAAGECRNLTGTLELMWQHCQECFEHSLALEQTLSRLQGTNFPIIVGRRPAALSATCGKENISRSALPSFASGNSLGKQKAIVVPGVGTAIQLANGELQVQYHDGAQLWVDGKHHVRYQYPDGQVVNYRDTDSIPKSIMAKMQLMPKVVRHLSAPLPAKQFHNLR

Features

Showing features for non-terminal residue, compositional bias.

Type
IDPosition(s)Description
Non-terminal residue1
Compositional bias348-363Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KB741112
EMBL· GenBank· DDBJ
ENN73796.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help