N6TZK4 · N6TZK4_DENPD
- ProteinSerine/threonine-protein kinase PLK4
- Gene109541525
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids764 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Catalytic activity
- L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 43 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | centriole | |
Cellular Component | centrosome | |
Cellular Component | cytoplasm | |
Cellular Component | kinetochore | |
Cellular Component | nucleus | |
Cellular Component | spindle pole | |
Molecular Function | ATP binding | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | mitotic spindle organization | |
Biological Process | protein phosphorylation | |
Biological Process | regulation of cell cycle |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSerine/threonine-protein kinase PLK4
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Coleoptera > Polyphaga > Cucujiformia > Curculionidae > Scolytinae > Dendroctonus
Accessions
- Primary accessionN6TZK4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 14-265 | Protein kinase | |||
Region | 338-377 | Disordered | |||
Compositional bias | 348-363 | Polar residues | |||
Domain | 430-547 | Cryptic POLO box 1 (CPB1) | |||
Domain | 548-655 | Cryptic POLO box 2 (CPB2) | |||
Domain | 675-753 | POLO box | |||
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusFragment
- Length764
- Mass (Da)85,336
- Last updated2013-06-26 v1
- Checksum96C01C6E97945DAB
Features
Showing features for non-terminal residue, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Non-terminal residue | 1 | ||||
Compositional bias | 348-363 | Polar residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KB741112 EMBL· GenBank· DDBJ | ENN73796.1 EMBL· GenBank· DDBJ | Genomic DNA |