N1Q0R1 · N1Q0R1_DOTSN
- ProteinCyanate hydratase
- Genecyn1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids169 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
Transcriptional coactivator that stimulates GCN4-dependent transcriptional activity by bridging the DNA-binding region of GCN4 and TBP (SPT15), thereby recruiting TBP to GCN4-bound promoters. Involved in induction of the ribosome quality control (RQC) pathway; a pathway that degrades nascent peptide chains during problematic translation. Required to prevent stalled ribosomes from frameshifting.
Catalytic activity
- cyanate + hydrogencarbonate + 3 H+ = NH4+ + 2 CO2
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 110 | ||||
Active site | 113 | ||||
Active site | 136 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | cyanate hydratase activity | |
Molecular Function | DNA binding | |
Biological Process | cyanate metabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCyanate hydratase
- EC number
- Short namesCyanase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Dothideomycetes > Dothideomycetidae > Mycosphaerellales > Mycosphaerellaceae > Dothistroma
Accessions
- Primary accessionN1Q0R1
Proteomes
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 97-169 | Cyanate lyase C-terminal | |||
Sequence similarities
Belongs to the MBF1 family.
Belongs to the cyanase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length169
- Mass (Da)18,669
- Last updated2013-06-26 v1
- MD5 Checksum62A2D781E6155FD38C51B18DF8E16058
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KB446536 EMBL· GenBank· DDBJ | EME48210.1 EMBL· GenBank· DDBJ | Genomic DNA |