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N1PN06 · N1PN06_DOTSN

Function

Catalytic activity

Features

Showing features for binding site, active site.

139550100150200250300350
Type
IDPosition(s)Description
Binding site130ATP (UniProtKB | ChEBI)
Binding site149ATP (UniProtKB | ChEBI)
Binding site198-200ATP (UniProtKB | ChEBI)
Active site243Proton acceptor
Binding site247-248ATP (UniProtKB | ChEBI)
Binding site261ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentchromosome passenger complex
Cellular Componentchromosome, telomeric region
Cellular Componentinner kinetochore
Cellular Componentmeiotic spindle midzone
Cellular Componentmitotic spindle midzone
Cellular Componentnucleolar peripheral inclusion body
Cellular Componentspindle microtubule
Molecular FunctionATP binding
Molecular Functionhistone H2AS1 kinase activity
Molecular Functionhistone H3S10 kinase activity
Biological Processattachment of meiotic spindle microtubules to kinetochore
Biological Processinterphase mitotic telomere clustering
Biological Processmeiotic spindle assembly checkpoint signaling
Biological Processmitotic sister chromatid biorientation
Biological Processmitotic spindle assembly checkpoint signaling
Biological Processmitotic spindle organization
Biological Processpositive regulation of G2/M transition of mitotic cell cycle
Biological Processpositive regulation of mitotic cell cycle spindle assembly checkpoint
Biological Processpositive regulation of mitotic chromosome condensation
Biological Processpositive regulation of mitotic sister chromatid arm separation
Biological Processpositive regulation of mitotic sister chromatid biorientation
Biological Processprotein phosphorylation
Biological Processregulation of mitotic cytokinesis
Biological Processregulation of spindle attachment to meiosis I kinetochore

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aurora kinase
  • EC number

Gene names

    • ORF names
      DOTSEDRAFT_171608

Organism names

Accessions

  • Primary accession
    N1PN06

Proteomes

PTM/Processing

Features

Showing features for cross-link.

TypeIDPosition(s)Description
Cross-link245Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-115Disordered
Compositional bias18-58Polar residues
Compositional bias67-98Polar residues
Domain120-373Protein kinase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    395
  • Mass (Da)
    44,629
  • Last updated
    2013-06-26 v1
  • MD5 Checksum
    793890470A333350D6D32749A1AC3FEF
MADIQTLEHRFEGISVQDENHDSTAQPAPKHQPKSSLSHAISLSNLGTSTTTAQSRMKLPLQKLAPNAGSKPTQTVLTKITLPSQAAQRPSTESRPSDPHSAVQREAPKPTPKQWHLGMFEIGKPLGKGKFGRVYLARERSSGFVCALKVLHKSELQAGKVEKQVRREIEIQSNLAHPNILRLYGHFHDTKRIFLILEFAGKGELYKHLRKAQRFPEPQAAGYVAQMASALKYLHKKHVMHRDIKPENILVGLHGEIKISDFGWSVHAPNNRRNTMCGTLDYLPPEMIKPGREENWYTEKVDLWSLGVLTYEFLVGEAPFEDTPVMTQRRIARGEMTVPSFVSPEARDLIKRLLVLDPEKRLNLDEVEVHPWIVKHCAGKKEKKQSNEGVQFVRG

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias18-58Polar residues
Compositional bias67-98Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KB446539
EMBL· GenBank· DDBJ
EME43765.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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