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N0DWW7 · N0DWW7_9BIVA

  • Protein
    ADP/ATP translocase
  • Gene
    ant
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane.
Catalyzes the exchange of ADP and ATP across the membrane.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular FunctionATP:ADP antiporter activity
Biological Processmitochondrial ADP transmembrane transport
Biological Processmitochondrial ATP transmembrane transport
Biological Processnegative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    ADP/ATP translocase
  • Alternative names
    • ADP,ATP carrier protein

Gene names

    • Name
      ant

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • 55.0
    • 56.0
    • 57.0
    • 58.0
    • 60.0
  • Taxonomic lineage
    Eukaryota > Metazoa > Spiralia > Lophotrochozoa > Mollusca > Bivalvia > Autobranchia > Heteroconchia > Euheterodonta > Imparidentia > Adapedonta > Solenoidea > Pharidae > Ensis

Accessions

  • Primary accession
    N0DWW7

Subcellular Location

Membrane
; Multi-pass membrane protein
Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane54-76Helical
Transmembrane91-112Helical

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for repeat.

TypeIDPosition(s)Description
Repeat1-83Solcar
Repeat89-135Solcar

Sequence similarities

Belongs to the mitochondrial carrier (TC 2.A.29) family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    135
  • Mass (Da)
    14,681
  • Last updated
    2013-06-26 v1
  • MD5 Checksum
    0F8EAB6A9A851629BEB0197C750C490E
GAAGAMSLVFVYSLDYCRTRLANDAKSGKKGGERQFNGMIDVYKKTIASDGVQGLYRGFVISCVGIIVYRGCYFGFYDTLKPIVLGDSKSFLASFALGYVVTISAGLVSYPIDTIRRRMMMTSGEAVKYKGSIDC

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue135

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HE661835
EMBL· GenBank· DDBJ
CCF79031.1
EMBL· GenBank· DDBJ
Genomic DNA
HE661836
EMBL· GenBank· DDBJ
CCF79032.1
EMBL· GenBank· DDBJ
Genomic DNA
HE661837
EMBL· GenBank· DDBJ
CCF79033.1
EMBL· GenBank· DDBJ
Genomic DNA
HE661838
EMBL· GenBank· DDBJ
CCF79034.1
EMBL· GenBank· DDBJ
Genomic DNA
HE661840
EMBL· GenBank· DDBJ
CCF79036.1
EMBL· GenBank· DDBJ
Genomic DNA
HE661841
EMBL· GenBank· DDBJ
CCF79037.1
EMBL· GenBank· DDBJ
Genomic DNA
HE661842
EMBL· GenBank· DDBJ
CCF79038.1
EMBL· GenBank· DDBJ
Genomic DNA
HE661843
EMBL· GenBank· DDBJ
CCF79039.1
EMBL· GenBank· DDBJ
Genomic DNA
HE661844
EMBL· GenBank· DDBJ
CCF79040.1
EMBL· GenBank· DDBJ
Genomic DNA
HE661845
EMBL· GenBank· DDBJ
CCF79041.1
EMBL· GenBank· DDBJ
Genomic DNA
HE661846
EMBL· GenBank· DDBJ
CCF79042.1
EMBL· GenBank· DDBJ
Genomic DNA
HE661847
EMBL· GenBank· DDBJ
CCF79043.1
EMBL· GenBank· DDBJ
Genomic DNA
HE661848
EMBL· GenBank· DDBJ
CCF79044.1
EMBL· GenBank· DDBJ
Genomic DNA
HE661849
EMBL· GenBank· DDBJ
CCF79045.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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