M9WC21 · M9WC21_9POXV

  • Protein
    Entry-fusion complex protein OPG094
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Component of the entry fusion complex (EFC), which consists of 11 proteins. During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Biological Processfusion of virus membrane with host plasma membrane

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Entry-fusion complex protein OPG094
  • Alternative names
    • Protein L5

Gene names

    • ORF names
      44.1rMVA_079
      , 44/47.1_rMVA_085
      , 47.1rMVA_084
      , 51.2rMVA_090
      , IKMOJFFE_00080
      , VAC_TP3_097
      , VAC_TP5_097
      , VACV_TT12_112
      , VACV_TT8_112
      , VACV_TT9_112

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • Tiantan
    • 44.1 rMVA
    • 44/47.1 rMVA
    • 47.1 rMVA
    • 51.2 rMVA
  • Taxonomic lineage
    Viruses > Varidnaviria > Bamfordvirae > Nucleocytoviricota > Pokkesviricetes > Chitovirales > Poxviridae > Chordopoxvirinae > Orthopoxvirus

Accessions

  • Primary accession
    M9WC21

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane30-47Helical

Keywords

  • Cellular component

Structure

3D structure databases

Family & Domains

Sequence similarities

Belongs to the orthopoxvirus OPG099 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    128
  • Mass (Da)
    15,058
  • Last updated
    2013-06-26 v1
  • MD5 Checksum
    8FE71EFDB952CBF121A7778F885907E9
MENVPNVYFNPVFIEPTFKHSLLSVYKHRLIVLFEVFIVFILIYVFFRSELNMFFMPKRKIPDPIDRLRRANLACEDDKLMIYGLPWMTTQTSALSINSKPIVYKDCAKLLRSINGSQPVSLNDVLRR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JX489135
EMBL· GenBank· DDBJ
AGJ91260.1
EMBL· GenBank· DDBJ
Genomic DNA
JX489136
EMBL· GenBank· DDBJ
AGJ91533.1
EMBL· GenBank· DDBJ
Genomic DNA
JX489139
EMBL· GenBank· DDBJ
AGJ92350.1
EMBL· GenBank· DDBJ
Genomic DNA
KC207810
EMBL· GenBank· DDBJ
AGK06561.1
EMBL· GenBank· DDBJ
Genomic DNA
KC207811
EMBL· GenBank· DDBJ
AGK06774.1
EMBL· GenBank· DDBJ
Genomic DNA
MK314710
EMBL· GenBank· DDBJ
QCI57109.1
EMBL· GenBank· DDBJ
Genomic DNA
MK314711
EMBL· GenBank· DDBJ
QCI57308.1
EMBL· GenBank· DDBJ
Genomic DNA
MK314712
EMBL· GenBank· DDBJ
QCI57504.1
EMBL· GenBank· DDBJ
Genomic DNA
MK314713
EMBL· GenBank· DDBJ
QCI57702.1
EMBL· GenBank· DDBJ
Genomic DNA
MN369532
EMBL· GenBank· DDBJ
QKE61233.1
EMBL· GenBank· DDBJ
Genomic DNA
MT648498
EMBL· GenBank· DDBJ
QMT29535.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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