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M9TKL3 · M9TKL3_AUSAL

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

137850100150200250300350
TypeIDPosition(s)Description
Binding site84Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site98Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site183Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site197Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site202a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      CYTB

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Crustacea > Multicrustacea > Malacostraca > Eumalacostraca > Eucarida > Decapoda > Pleocyemata > Brachyura > Eubrachyura > Bythograeoidea > Bythograeidae > Austinograea

Accessions

  • Primary accession
    M9TKL3

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane31-57Helical
Transmembrane78-99Helical
Transmembrane111-134Helical
Transmembrane141-159Helical
Transmembrane179-201Helical
Transmembrane230-251Helical
Transmembrane289-309Helical
Transmembrane321-341Helical
Transmembrane348-373Helical

Keywords

Interaction

Subunit

The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-210Cytochrome b/b6 N-terminal region profile
Domain211-378Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    378
  • Mass (Da)
    42,977
  • Last updated
    2013-06-26 v1
  • MD5 Checksum
    0A1F80BB3464A1FF6AEFED0829A317B9
MTTPMRKSHPLFKIMNNALVDMPLPSNISTLWNFGSLLGLCLVIQIATGLFLSMHYIAHIDLAFSSVAHICRDVNYGWLLRTTHANGASFFFICLYIHIGRGMFYGSYMMLHAWMVGVIILFMIMATAFLGYVLPWGQMSFWGATVITNLFSAIPYVGTDLVQWIWGGFSVDNATLTRFFTFHFILPFIAAAMSLIHILFLHQTGANNPLGISSQVDKLPFHPYFTFKDIVGFIVMLSTLLLLSLLNPYLLGDPDNFVPANPLVTPIHIQPEWYFLFAYAILRSIPNKLGGVIALVASVMILMILPFSHVSKFRSLTFYPLNQIMFWFLVAILFLLTWIGARPVEDPYIITGQILTILYFSFFLINPLSLLWWDKMLK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KC851803
EMBL· GenBank· DDBJ
AGJ50506.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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