M9PH20 · M9PH20_DROME
- ProteinDiacylglycerol kinase
- GenerdgA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1460 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H+
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | ATP-dependent diacylglycerol kinase activity | |
Molecular Function | metal ion binding | |
Biological Process | protein kinase C-activating G protein-coupled receptor signaling pathway |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDiacylglycerol kinase
- EC number
- Short namesDAG kinase
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionM9PH20
Proteomes
Organism-specific databases
Expression
Gene expression databases
Family & Domains
Features
Showing features for compositional bias, region, domain, repeat.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-75 | Polar residues | ||||
Sequence: MQQQQQPSIDQLPEPTASTSNSATTKPTIATATTSTTTTSGNNFHQQLQATTAATMQRLRTTFTRSRTPTGAEMK | ||||||
Region | 1-87 | Disordered | ||||
Sequence: MQQQQQPSIDQLPEPTASTSNSATTKPTIATATTSTTTTSGNNFHQQLQATTAATMQRLRTTFTRSRTPTGAEMKMQNSLEVPKQVK | ||||||
Compositional bias | 103-123 | Polar residues | ||||
Sequence: RASSSLLKQQSSSSASADERS | ||||||
Region | 103-126 | Disordered | ||||
Sequence: RASSSLLKQQSSSSASADERSSEA | ||||||
Compositional bias | 139-154 | Polar residues | ||||
Sequence: RSHSFDSATASAGSDD | ||||||
Region | 139-177 | Disordered | ||||
Sequence: RSHSFDSATASAGSDDSGTFLEVPRRLKARRSSSTKTPP | ||||||
Region | 210-342 | Disordered | ||||
Sequence: YSNTSSEASEDEDEVEGHNAEEEEEGSAAIEDAEEETTEAATEEADEDPRTEVESEHDHDPDDDAALEMDIRIGNMSQGSSIEESRARLPRQMRRHTIGSSSVTSASEDEGLEGSDNGSPHFGNTLLPPQPTT | ||||||
Compositional bias | 216-260 | Acidic residues | ||||
Sequence: EASEDEDEVEGHNAEEEEEGSAAIEDAEEETTEAATEEADEDPRT | ||||||
Compositional bias | 261-278 | Basic and acidic residues | ||||
Sequence: EVESEHDHDPDDDAALEM | ||||||
Compositional bias | 304-342 | Polar residues | ||||
Sequence: RHTIGSSSVTSASEDEGLEGSDNGSPHFGNTLLPPQPTT | ||||||
Region | 761-802 | Disordered | ||||
Sequence: NNAASGSGGGGAGGGAGGGGGKSKKQTQRRQKGKEEKKEPRA | ||||||
Domain | 811-947 | DAGKc | ||||
Sequence: PEVIPVIVFINPKSGGNQGHKLLGKFQHLLNPRQVFDLTQGGPKMGLDMFRKAPNLRVLACGGDGTVGWVLSVLDQIQPPLQPAPAVGVLPLGTGNDLARALGWGGGYTDEPIGKILREIGMSQCVLMDRWRVKVTP | ||||||
Compositional bias | 1267-1295 | Polar residues | ||||
Sequence: TPDQERSFAAFSQRQAQNERRQMDQAQGR | ||||||
Region | 1267-1305 | Disordered | ||||
Sequence: TPDQERSFAAFSQRQAQNERRQMDQAQGRGPGSTDEDLQ | ||||||
Repeat | 1356-1377 | ANK | ||||
Sequence: NGQTALHFACKYNHRDIVKYII | ||||||
Repeat | 1392-1424 | ANK | ||||
Sequence: LGQTALHIAAEQNRRDICVMLVAAGAHLDTLDS |
Sequence similarities
Belongs to the eukaryotic diacylglycerol kinase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,460
- Mass (Da)160,498
- Last updated2013-06-26 v1
- Checksum9BFFF9E82A0478A2
Computationally mapped potential isoform sequences
There are 8 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q09103 | DGK2_DROME | rdgA | 1457 | ||
A0A6H2EFG8 | A0A6H2EFG8_DROME | rdgA | 1365 | ||
M9PHG3 | M9PHG3_DROME | rdgA | 1462 | ||
X2JE67 | X2JE67_DROME | rdgA | 1307 | ||
M9MSN3 | M9MSN3_DROME | rdgA | 1009 | ||
M9MS31 | M9MS31_DROME | rdgA | 1452 | ||
X2JEJ9 | X2JEJ9_DROME | rdgA | 1314 | ||
A0A023GPM5 | A0A023GPM5_DROME | rdgA | 991 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-75 | Polar residues | ||||
Sequence: MQQQQQPSIDQLPEPTASTSNSATTKPTIATATTSTTTTSGNNFHQQLQATTAATMQRLRTTFTRSRTPTGAEMK | ||||||
Compositional bias | 103-123 | Polar residues | ||||
Sequence: RASSSLLKQQSSSSASADERS | ||||||
Compositional bias | 139-154 | Polar residues | ||||
Sequence: RSHSFDSATASAGSDD | ||||||
Compositional bias | 216-260 | Acidic residues | ||||
Sequence: EASEDEDEVEGHNAEEEEEGSAAIEDAEEETTEAATEEADEDPRT | ||||||
Compositional bias | 261-278 | Basic and acidic residues | ||||
Sequence: EVESEHDHDPDDDAALEM | ||||||
Compositional bias | 304-342 | Polar residues | ||||
Sequence: RHTIGSSSVTSASEDEGLEGSDNGSPHFGNTLLPPQPTT | ||||||
Compositional bias | 1267-1295 | Polar residues | ||||
Sequence: TPDQERSFAAFSQRQAQNERRQMDQAQGR |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE014298 EMBL· GenBank· DDBJ | AGB95210.1 EMBL· GenBank· DDBJ | Genomic DNA |