M9PG82 · M9PG82_DROME
- ProteinEnoyl-CoA hydratase, mitochondrial
- GeneHIPP1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids924 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Catalytic activity
- (2E)-2-methylpropenoyl-CoA + H2O = (S)-3-hydroxyisobutanoyl-CoAThis reaction proceeds in the forward direction.
- (3S)-3-hydroxybutanoyl-CoA = (2E)-butenoyl-CoA + H2OThis reaction proceeds in the backward direction.
- 3-hydroxybutanoyl-CoA = (2E)-butenoyl-CoA + H2OThis reaction proceeds in the backward direction.
- 3-hydroxyisovaleryl-CoA = 3-methyl-(2E)-butenoyl-CoA + H2OThis reaction proceeds in the backward direction.
- 3-hydroxypropanoyl-CoA = acryloyl-CoA + H2OThis reaction proceeds in the backward direction.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3-hydroxypropionyl-CoA dehydratase activity | |
Molecular Function | chromatin insulator sequence binding | |
Molecular Function | crotonyl-CoA hydratase activity |
Names & Taxonomy
Protein names
- Recommended nameEnoyl-CoA hydratase, mitochondrial
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionM9PG82
Proteomes
Organism-specific databases
Expression
Gene expression databases
Interaction
Subunit
Homohexamer; dimer of trimers.
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-17 | Polar residues | |||
Region | 1-25 | Disordered | |||
Compositional bias | 40-54 | Polar residues | |||
Region | 40-65 | Disordered | |||
Region | 80-113 | Disordered | |||
Region | 190-267 | Disordered | |||
Compositional bias | 215-229 | Polar residues | |||
Compositional bias | 409-430 | Polar residues | |||
Region | 409-485 | Disordered | |||
Compositional bias | 465-479 | Polar residues | |||
Region | 533-578 | Disordered | |||
Compositional bias | 552-574 | Polar residues | |||
Region | 592-659 | Disordered | |||
Compositional bias | 594-618 | Polar residues | |||
Compositional bias | 637-659 | Polar residues | |||
Sequence similarities
Belongs to the enoyl-CoA hydratase/isomerase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length924
- Mass (Da)99,752
- Last updated2013-06-26 v1
- Checksum034F674046D5EA66
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-17 | Polar residues | |||
Compositional bias | 40-54 | Polar residues | |||
Compositional bias | 215-229 | Polar residues | |||
Compositional bias | 409-430 | Polar residues | |||
Compositional bias | 465-479 | Polar residues | |||
Compositional bias | 552-574 | Polar residues | |||
Compositional bias | 594-618 | Polar residues | |||
Compositional bias | 637-659 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE014296 EMBL· GenBank· DDBJ | AGB94819.1 EMBL· GenBank· DDBJ | Genomic DNA |