M9PG82 · M9PG82_DROME

Function

Catalytic activity

  • (2E)-2-methylpropenoyl-CoA + H2O = (S)-3-hydroxyisobutanoyl-CoA
    This reaction proceeds in the forward direction.
  • (3S)-3-hydroxybutanoyl-CoA = (2E)-butenoyl-CoA + H2O
    This reaction proceeds in the backward direction.
  • 3-hydroxybutanoyl-CoA = (2E)-butenoyl-CoA + H2O
    This reaction proceeds in the backward direction.
  • 3-hydroxyisovaleryl-CoA = 3-methyl-(2E)-butenoyl-CoA + H2O
    This reaction proceeds in the backward direction.
  • 3-hydroxypropanoyl-CoA = acryloyl-CoA + H2O
    This reaction proceeds in the backward direction.
  • a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O
    This reaction proceeds in the backward direction.
    EC:4.2.1.17 (UniProtKB | ENZYME | Rhea)

GO annotations

AspectTerm
Molecular Function3-hydroxypropionyl-CoA dehydratase activity
Molecular Functionchromatin insulator sequence binding
Molecular Functioncrotonyl-CoA hydratase activity

Names & Taxonomy

Protein names

  • Recommended name
    Enoyl-CoA hydratase, mitochondrial
  • Alternative names
    • Enoyl-CoA hydratase 1
    • Short-chain enoyl-CoA hydratase

Gene names

    • Name
      HIPP1
    • Synonyms
      Dmel\CG3680
      , HiPP1
      , Hipp1
    • ORF names
      CG3680
      , Dmel_CG3680

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    M9PG82

Proteomes

Organism-specific databases

Expression

Gene expression databases

Interaction

Subunit

Homohexamer; dimer of trimers.

Structure

Family & Domains

Features

Showing features for compositional bias, region.

Type
IDPosition(s)Description
Compositional bias1-17Polar residues
Region1-25Disordered
Compositional bias40-54Polar residues
Region40-65Disordered
Region80-113Disordered
Region190-267Disordered
Compositional bias215-229Polar residues
Compositional bias409-430Polar residues
Region409-485Disordered
Compositional bias465-479Polar residues
Region533-578Disordered
Compositional bias552-574Polar residues
Region592-659Disordered
Compositional bias594-618Polar residues
Compositional bias637-659Polar residues

Sequence similarities

Belongs to the enoyl-CoA hydratase/isomerase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    924
  • Mass (Da)
    99,752
  • Last updated
    2013-06-26 v1
  • Checksum
    034F674046D5EA66
MEQVSDSAVTTLESTQAEEPPPGVEKVETLELKTAALETLSESAGPTDLENELANLNGSEEGPGLDELSTLEREIAKLHNIRPPDAASEVKDSDTPIALADNGGLEPRQAPDEAKCRTPIIEEGNAASGNGQSSESPLEEVDLIALLKGTDTSHDQPTGEEKCTLEKALSELDGVGEDGDVGVTIEGEGQFEIMEIDDDEGESSSRKASPKVPASKPIKSNSLPSISKHKLSPEQARAVALEQMAGLKPKSRRKEPPAPPSVVAPIDIVSSLNDDWDDYDSEEDKSASALVTEVITLPSAHVVTKKPPLPVKKLSSPVKHSPNSAILLNNKISGVKVMLKTVSQKQLAASTGAAAEKTKPTVVVSPPKETEEHTTGFKRMRVIKRKIIWDPDVPETKKSFAQYASTKAACPAPTTPKTTVKSISPTTTTKKEVAPKKRSATPTARSTKAGTPVGGTERGPSPVKRRAQTPNTGLANGGTQKKKKVSEIDRLMGDEGAANMIHAVEHEQRELSGGEVSNKPLMRKRAMTITGRAARVAVEPTPPKKESAQSAAKRTPADSVFTKATANTSARKPRASDSWDYVYKQRASEESMIMRRRSNSSYSSNASVSRNSLDNRPGAANLSDDAGEGSDPSFKFVKPVSKSSQRGGEDTSSHTLANDMKANNGSELVCLHKVNKVAHLVIHTERGNFGHTYSKQLLEQLNDTLSSVARKGEFNTVLLTVEGPQFCQGIDCQELIQGSLEKRKDSASQLAVALKCYLRTLATFPKPLVAGIVGSQINLGVMQLPFADYVVASDDCSFETNYAKLGQLPEGYALWHGHQRVSSEVHSRLFLMGERLFATELLESNSFVDKICKARNVNEMALAKAKQISTSSAEMYRTLKKLNHSAVNVTKFPRLDEELKVIGEQWVTADCLANFKRYLNDVDF

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q9VPB0Q9VPB0_DROMEHIPP1926
M9PG20M9PG20_DROMEHIPP1925
M9PID3M9PID3_DROMEHIPP1923

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-17Polar residues
Compositional bias40-54Polar residues
Compositional bias215-229Polar residues
Compositional bias409-430Polar residues
Compositional bias465-479Polar residues
Compositional bias552-574Polar residues
Compositional bias594-618Polar residues
Compositional bias637-659Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE014296
EMBL· GenBank· DDBJ
AGB94819.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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