M9PCN5 · M9PCN5_DROME
- ProteinPH-sensitive chloride channel 1, isoform O
- GenepHCl-1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids929 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | neuron projection | |
Cellular Component | plasma membrane | |
Cellular Component | synapse | |
Cellular Component | transmembrane transporter complex | |
Molecular Function | extracellular ligand-gated monoatomic ion channel activity | |
Molecular Function | neurotransmitter receptor activity | |
Molecular Function | pH-gated chloride channel activity | |
Molecular Function | transmembrane signaling receptor activity | |
Biological Process | chloride transmembrane transport |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionM9PCN5
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 257-277 | Helical | ||||
Sequence: IIANVGATAAATSAAAFQYLG | ||||||
Transmembrane | 289-310 | Helical | ||||
Sequence: FYAASSVLLMLCYLTTASTAAA | ||||||
Transmembrane | 538-561 | Helical | ||||
Sequence: AFYFTTVFIPGIILVTSSFITFWL | ||||||
Transmembrane | 602-624 | Helical | ||||
Sequence: VWDGVCMCFIYASLLEFVCVNYV | ||||||
Transmembrane | 904-925 | Helical | ||||
Sequence: VIARITFPTAYAIFLIFFFVHY |
Keywords
- Cellular component
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-68 | Disordered | ||||
Sequence: MGCVFEAAKEQPHKPRSRQLRRNQCRGKAEKAAAGTRGKVAVRGNNDKPAEDIKIKDNYQQNHKTQTE | ||||||
Compositional bias | 44-61 | Basic and acidic residues | ||||
Sequence: GNNDKPAEDIKIKDNYQQ | ||||||
Region | 84-104 | Disordered | ||||
Sequence: GAETETETEAEAQKEPATGPE | ||||||
Region | 121-142 | Disordered | ||||
Sequence: QENNKHSSSQVAETHKDEGEDA | ||||||
Compositional bias | 172-192 | Basic and acidic residues | ||||
Sequence: HEDGQHWQQHNVRRRRRQPDP | ||||||
Region | 172-196 | Disordered | ||||
Sequence: HEDGQHWQQHNVRRRRRQPDPAAHP | ||||||
Domain | 331-524 | Neurotransmitter-gated ion-channel ligand-binding | ||||
Sequence: KEILDLLLEKKRYDKRLLPPVNGTLTVNVNVLLLSLASPDESSLKYEVEFLLNQQWNDPRLQYGNKSHYDFLNALHHHDSIWTPDTYFIMHGDFKDPIIPMHFALRIFRNGTITYAMRRHLILSCQGSLHIFPFDDPKCSFSMESISYEEAQIKYVWKNDEDTLRKSPSLTTLNAYLIKNQTTACDQNSWRGNY | ||||||
Domain | 545-921 | Neurotransmitter-gated ion-channel transmembrane | ||||
Sequence: FIPGIILVTSSFITFWLEWNAVPARSMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPLHNVVYRPGENPVTQASAAATPAMSMMGGATPMSSGTPAASSSVATPGTPRITDPEEFFGGGMRWQEAHGGIIGAAVQNLRARSIKRKAARSPSTSISPHPSGRPTEHIYEEPGGSTSGVTSTKVKFKDELKEEQPEEAESSTKLRRSVATSTPALVVRIEAEIDPEAEDKPIQDMEMTERQLSLPLKPPRRKASRSNSPASVYSDAFENVEATPGEKRQNAGAPNEIVACTTCGGSNSPCTHSANNGCATETCFVQVRKKEPPHPIRVAKTIDVIARITFPTAYAIFLIFF | ||||||
Compositional bias | 660-678 | Polar residues | ||||
Sequence: TPMSSGTPAASSSVATPGT | ||||||
Region | 660-681 | Disordered | ||||
Sequence: TPMSSGTPAASSSVATPGTPRI | ||||||
Region | 713-779 | Disordered | ||||
Sequence: SIKRKAARSPSTSISPHPSGRPTEHIYEEPGGSTSGVTSTKVKFKDELKEEQPEEAESSTKLRRSVA | ||||||
Compositional bias | 754-773 | Basic and acidic residues | ||||
Sequence: VKFKDELKEEQPEEAESSTK | ||||||
Region | 811-836 | Disordered | ||||
Sequence: QLSLPLKPPRRKASRSNSPASVYSDA |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length929
- Mass (Da)102,681
- Last updated2013-06-26 v1
- Checksum8EF369551912593E
Computationally mapped potential isoform sequences
There are 16 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
M9PI70 | M9PI70_DROME | pHCl-1 | 978 | ||
M9PCN0 | M9PCN0_DROME | pHCl-1 | 772 | ||
A0A4D6K8E5 | A0A4D6K8E5_DROME | pHCl-1 | 774 | ||
Q2PDY9 | Q2PDY9_DROME | pHCl-1 | 779 | ||
Q2PDZ0 | Q2PDZ0_DROME | pHCl-1 | 762 | ||
M9PFR7 | M9PFR7_DROME | pHCl-1 | 747 | ||
M9PFD4 | M9PFD4_DROME | pHCl-1 | 746 | ||
M9PFD7 | M9PFD7_DROME | pHCl-1 | 754 | ||
M9PFL8 | M9PFL8_DROME | pHCl-1 | 954 | ||
X2JGQ0 | X2JGQ0_DROME | pHCl-1 | 755 | ||
M9NEB0 | M9NEB0_DROME | pHCl-1 | 762 | ||
E1JI08 | E1JI08_DROME | pHCl-1 | 681 | ||
Q9VUV2 | Q9VUV2_DROME | pHCl-1 | 737 | ||
Q9VUV3 | Q9VUV3_DROME | pHCl-1 | 637 | ||
M9NFY2 | M9NFY2_DROME | pHCl-1 | 754 | ||
X2JCG3 | X2JCG3_DROME | pHCl-1 | 770 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 44-61 | Basic and acidic residues | ||||
Sequence: GNNDKPAEDIKIKDNYQQ | ||||||
Compositional bias | 172-192 | Basic and acidic residues | ||||
Sequence: HEDGQHWQQHNVRRRRRQPDP | ||||||
Compositional bias | 660-678 | Polar residues | ||||
Sequence: TPMSSGTPAASSSVATPGT | ||||||
Compositional bias | 754-773 | Basic and acidic residues | ||||
Sequence: VKFKDELKEEQPEEAESSTK |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE014296 EMBL· GenBank· DDBJ | AGB94592.1 EMBL· GenBank· DDBJ | Genomic DNA |