M9NGR9 · M9NGR9_DROME
- ProteinCa[2+]-channel protein alpha[[1]] subunit T, isoform D
- GeneCa-alpha1T
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids3180 (go to sequence)
- Protein existencePredicted
- Annotation score4/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | neuron projection | |
Cellular Component | voltage-gated calcium channel complex | |
Cellular Component | voltage-gated sodium channel complex | |
Molecular Function | low voltage-gated calcium channel activity | |
Biological Process | calcium ion import | |
Biological Process | calcium ion transmembrane transport | |
Biological Process | membrane depolarization during action potential | |
Biological Process | neuronal action potential | |
Biological Process | sodium ion transmembrane transport |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionM9NGR9
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 430-453 | Helical | ||||
Sequence: MLGNVLLLCFFVFFIFGIIGVQLW | ||||||
Transmembrane | 552-570 | Helical | ||||
Sequence: ISFDNIGMAWVAIFLVISL | ||||||
Transmembrane | 590-615 | Helical | ||||
Sequence: IYFVLLIVIGSFFMINLCLVVIATQF | ||||||
Transmembrane | 1224-1242 | Helical | ||||
Sequence: YFQQGILLAILINTLSMGI | ||||||
Transmembrane | 1254-1275 | Helical | ||||
Sequence: IVETSNVVFSGIFAVEMLLKVV | ||||||
Transmembrane | 1287-1307 | Helical | ||||
Sequence: FNVFDGIIVILSAIEICQTFM | ||||||
Transmembrane | 1353-1376 | Helical | ||||
Sequence: VAVFFSLLVLFIFIFSILGMNLFG | ||||||
Transmembrane | 1429-1452 | Helical | ||||
Sequence: ALYFVALMTFGNYVLFNLLVAILV | ||||||
Transmembrane | 2169-2197 | Helical | ||||
Sequence: LFLATANYVFTVVFTVEMFIKVVATGMFY | ||||||
Transmembrane | 2276-2295 | Helical | ||||
Sequence: IVLICCTFFIIFGILGVQLF | ||||||
Transmembrane | 2376-2399 | Helical | ||||
Sequence: LLYFIAFILLVGFFVLNMFVGVVV | ||||||
Transmembrane | 2456-2477 | Helical | ||||
Sequence: YFDLAIAAVIGLNVVTMAMEYY | ||||||
Transmembrane | 2489-2511 | Helical | ||||
Sequence: IFNYFFTAVFILEANMKLVALGW | ||||||
Transmembrane | 2592-2612 | Helical | ||||
Sequence: LGLLFFLLFFIFAALGVELFG | ||||||
Transmembrane | 2677-2703 | Helical | ||||
Sequence: VIAPIFFVIFVLMAQFVLVNVVVAVLM |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Expression
Gene expression databases
Family & Domains
Features
Showing features for region, compositional bias, domain, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-272 | Disordered | ||||
Sequence: MLPQPAAAVATATTTTTQSATSATSTAATSAAAAAARNGQRRRVAAATEGCNSNIGNSNSKLSSNTTTNTTKRVSQMHSNEEPPMTVIVDGGGGSNVSVSGGSSHRRGSQRLRKTSSSSANAKSASANPTERTSSGQRSSHRQTSNASDGGGSSRRRYQGKEHHDRRDRQDRQDRQDRQERSDRHERRDRRDEQQAARRRTGRRHSGASSLSDAAAATAAGRSRSRGGGRTGGAVSSSTGSSCNGSCSSDDGDSSHTSSSSSSSSSGEPNLP | ||||||
Compositional bias | 8-33 | Polar residues | ||||
Sequence: AVATATTTTTQSATSATSTAATSAAA | ||||||
Compositional bias | 50-82 | Polar residues | ||||
Sequence: GCNSNIGNSNSKLSSNTTTNTTKRVSQMHSNEE | ||||||
Compositional bias | 113-153 | Polar residues | ||||
Sequence: RKTSSSSANAKSASANPTERTSSGQRSSHRQTSNASDGGGS | ||||||
Compositional bias | 155-200 | Basic and acidic residues | ||||
Sequence: RRRYQGKEHHDRRDRQDRQDRQDRQERSDRHERRDRRDEQQAARRR | ||||||
Compositional bias | 230-270 | Polar residues | ||||
Sequence: RTGGAVSSSTGSSCNGSCSSDDGDSSHTSSSSSSSSSGEPN | ||||||
Domain | 300-622 | Ion transport | ||||
Sequence: NPWFERVSILVILLNCITLGMYQPCVDDACVTNRCKILQIFDDIIFAFFALEMTIKMVAMGICGKNTYLADSWNRLDFFIVLAGLLEYVMHVENLNLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWEGILRQRCSLMRTEGMVYPLTLSQYYEFSKDQDYICSTPNDSGMHLCGNFPPYRIGSLVCNEEAKLFDFNEPTNTSCVNWNQYYTTCKQSGENPFQGTISFDNIGMAWVAIFLVISLEGWTDIMYYVQDAHSFWDWIYFVLLIVIGSFFMINLCLVVIATQFSETKKRE | ||||||
Region | 733-767 | Disordered | ||||
Sequence: SASNNINNNNNNNSNSSNHNGSGNHTAAGGGNNNN | ||||||
Compositional bias | 793-850 | Polar residues | ||||
Sequence: VTMSSAHHQQHQLLQHQQQQHQNQQQQQQQQQHSSSDNTEQSLAPDGLPRSSSLKKST | ||||||
Region | 793-861 | Disordered | ||||
Sequence: VTMSSAHHQQHQLLQHQQQQHQNQQQQQQQQQHSSSDNTEQSLAPDGLPRSSSLKKSTAHHQLKPEGSA | ||||||
Region | 950-976 | Disordered | ||||
Sequence: TGSGSGNNNHQNGGASGGAGTGGTTEK | ||||||
Region | 1118-1162 | Disordered | ||||
Sequence: ANHRRKEHHQQSHHHHNNNNTTSHSRNYRSRQGQGNSRMREPRAP | ||||||
Compositional bias | 1133-1158 | Polar residues | ||||
Sequence: HNNNNTTSHSRNYRSRQGQGNSRMRE | ||||||
Domain | 1222-1462 | Ion transport | ||||
Sequence: HKYFQQGILLAILINTLSMGIEYHNQPPELTAIVETSNVVFSGIFAVEMLLKVVAEGPFRYIANGFNVFDGIIVILSAIEICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFMPNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMNLFGCKFCEKVNGEMICDRKNFDSLLWALVTVFQILTQEDWNVVLFNGMEKTSHWAALYFVALMTFGNYVLFNLLVAILVEGFSSERNER | ||||||
Region | 1483-1503 | Disordered | ||||
Sequence: YSDGMYDESRSEADSSTTNDS | ||||||
Compositional bias | 1552-1566 | Polar residues | ||||
Sequence: PASSAAPSASGTSGA | ||||||
Region | 1552-1678 | Disordered | ||||
Sequence: PASSAAPSASGTSGASAPGDRERDRDRDRDRERDRDRDRERDREAGGGGKEEGAQHAKPRGGLKKTYSIKERRSEAPRLSKIRLARDPPIITTTAATPQDSPSTTLEPGMSFRQWGDMEPPSPPSPS | ||||||
Compositional bias | 1569-1633 | Basic and acidic residues | ||||
Sequence: PGDRERDRDRDRDRERDRDRDRERDREAGGGGKEEGAQHAKPRGGLKKTYSIKERRSEAPRLSKI | ||||||
Compositional bias | 1643-1661 | Polar residues | ||||
Sequence: TTTAATPQDSPSTTLEPGM | ||||||
Region | 1772-1909 | Disordered | ||||
Sequence: AQSQSHSLNDVSVGSSPGGEIPATGMSRNANTGASTSGSSSSERLPLAPPPQQGSFKQRLRRGSSKKRRASALALATDDNPARRTLDNQARRTQDEEEEQQQLNNGGDNSCLLRNSNAVVSGSSSGTKETNRLSPQNS | ||||||
Compositional bias | 1796-1819 | Polar residues | ||||
Sequence: GMSRNANTGASTSGSSSSERLPLA | ||||||
Compositional bias | 1855-1870 | Basic and acidic residues | ||||
Sequence: RTLDNQARRTQDEEEE | ||||||
Compositional bias | 1874-1909 | Polar residues | ||||
Sequence: LNNGGDNSCLLRNSNAVVSGSSSGTKETNRLSPQNS | ||||||
Coiled coil | 2022-2049 | |||||
Sequence: ISHYNLKKRLEEKELQQLQQLHQQQLLQ | ||||||
Compositional bias | 2050-2082 | Polar residues | ||||
Sequence: QRQDSFSSTTQQQQQQLQQHRLSKDQQQLAMQP | ||||||
Region | 2050-2086 | Disordered | ||||
Sequence: QRQDSFSSTTQQQQQQLQQHRLSKDQQQLAMQPHSMV | ||||||
Domain | 2137-2409 | Ion transport | ||||
Sequence: KWFDNVVLLFIALNCITLAMERPNIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSLISESSPRIFGILRVFRLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGTFYYCEGENIKGVRNADECRRIPGNVWTNRKYNFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREEQ | ||||||
Domain | 2454-2712 | Ion transport | ||||
Sequence: SKYFDLAIAAVIGLNVVTMAMEYYKMPSGLKYALKIFNYFFTAVFILEANMKLVALGWKLYLKDRWNQLDVGIVLLSIVGIVLEELETNTHQIIPINPTIIRVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDEIPCQGLGEHAHFANFGMAFLTLFRVATGDNWNGIMKDTLRDNCDDAADCVRNCCVSSVIAPIFFVIFVLMAQFVLVNVVVAVLMKHLEESHKQ | ||||||
Region | 3047-3067 | Disordered | ||||
Sequence: LSVPRSMPPRSRSGSTKQLFK | ||||||
Compositional bias | 3137-3169 | Basic and acidic residues | ||||
Sequence: ISERRRMDQREQREPEQDQDNEAEDRDSDYKEL | ||||||
Region | 3137-3180 | Disordered | ||||
Sequence: ISERRRMDQREQREPEQDQDNEAEDRDSDYKELLLVKSPQSSMD |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length3,180
- Mass (Da)351,342
- Last updated2013-06-26 v1
- ChecksumB8771866DC4765B4
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 8-33 | Polar residues | ||||
Sequence: AVATATTTTTQSATSATSTAATSAAA | ||||||
Compositional bias | 50-82 | Polar residues | ||||
Sequence: GCNSNIGNSNSKLSSNTTTNTTKRVSQMHSNEE | ||||||
Compositional bias | 113-153 | Polar residues | ||||
Sequence: RKTSSSSANAKSASANPTERTSSGQRSSHRQTSNASDGGGS | ||||||
Compositional bias | 155-200 | Basic and acidic residues | ||||
Sequence: RRRYQGKEHHDRRDRQDRQDRQDRQERSDRHERRDRRDEQQAARRR | ||||||
Compositional bias | 230-270 | Polar residues | ||||
Sequence: RTGGAVSSSTGSSCNGSCSSDDGDSSHTSSSSSSSSSGEPN | ||||||
Compositional bias | 793-850 | Polar residues | ||||
Sequence: VTMSSAHHQQHQLLQHQQQQHQNQQQQQQQQQHSSSDNTEQSLAPDGLPRSSSLKKST | ||||||
Compositional bias | 1133-1158 | Polar residues | ||||
Sequence: HNNNNTTSHSRNYRSRQGQGNSRMRE | ||||||
Compositional bias | 1552-1566 | Polar residues | ||||
Sequence: PASSAAPSASGTSGA | ||||||
Compositional bias | 1569-1633 | Basic and acidic residues | ||||
Sequence: PGDRERDRDRDRDRERDRDRDRERDREAGGGGKEEGAQHAKPRGGLKKTYSIKERRSEAPRLSKI | ||||||
Compositional bias | 1643-1661 | Polar residues | ||||
Sequence: TTTAATPQDSPSTTLEPGM | ||||||
Compositional bias | 1796-1819 | Polar residues | ||||
Sequence: GMSRNANTGASTSGSSSSERLPLA | ||||||
Compositional bias | 1855-1870 | Basic and acidic residues | ||||
Sequence: RTLDNQARRTQDEEEE | ||||||
Compositional bias | 1874-1909 | Polar residues | ||||
Sequence: LNNGGDNSCLLRNSNAVVSGSSSGTKETNRLSPQNS | ||||||
Compositional bias | 2050-2082 | Polar residues | ||||
Sequence: QRQDSFSSTTQQQQQQLQQHRLSKDQQQLAMQP | ||||||
Compositional bias | 3137-3169 | Basic and acidic residues | ||||
Sequence: ISERRRMDQREQREPEQDQDNEAEDRDSDYKEL |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE014298 EMBL· GenBank· DDBJ | AFH07258.1 EMBL· GenBank· DDBJ | Genomic DNA |