M9NGL3 · M9NGL3_DROME
- ProteinTerribly reduced optic lobes, isoform AM
- Genetrol
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids3967 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | basement membrane | |
Cellular Component | plasma membrane | |
Biological Process | animal organ development | |
Biological Process | defasciculation of motor neuron axon | |
Biological Process | maintenance of epithelial cell apical/basal polarity | |
Biological Process | motor neuron axon guidance | |
Biological Process | positive regulation of semaphorin-plexin signaling pathway | |
Biological Process | response to anesthetic |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionM9NGL3
Proteomes
Organism-specific databases
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Disulfide bond | 386↔401 | |||||
Sequence: CDREIQCPDGEDEEYC | ||||||
Disulfide bond | 425↔440 | |||||
Sequence: CDGSIDCLDQTDEAGC | ||||||
Disulfide bond | 492↔504 | |||||
Sequence: CQANEFRCNNGDC | ||||||
Disulfide bond | 499↔517 | |||||
Sequence: CNNGDCIDARKRCNNVSDC | ||||||
Disulfide bond | 551↔566 | |||||
Sequence: CDGHSDCSDGDDEEHC | ||||||
Disulfide bond | 576↔588 | |||||
Sequence: CRFDEFHCGTGEC | ||||||
Disulfide bond | 583↔601 | |||||
Sequence: CGTGECIPMRQVCDNIYDC | ||||||
Disulfide bond | 595↔610 | |||||
Sequence: CDNIYDCNDYSDEVNC | ||||||
Disulfide bond | 684↔699 | |||||
Sequence: CDGFYHCNDMSDEKSC | ||||||
Disulfide bond | 768↔780 | |||||
Sequence: CYANQFRCNNGDC | ||||||
Disulfide bond | 775↔793 | |||||
Sequence: CNNGDCVSGSAPCNGYSEC | ||||||
Disulfide bond | 787↔802 | |||||
Sequence: CNGYSECSDHSDELNC | ||||||
Disulfide bond | 808↔820 | |||||
Sequence: CLPNQFRCNSGQC | ||||||
Disulfide bond | 815↔833 | |||||
Sequence: CNSGQCVSSSVRCNGRTDC | ||||||
Disulfide bond | 827↔842 | |||||
Sequence: CNGRTDCQDSSDEQNC | ||||||
Disulfide bond | 955↔967 | |||||
Sequence: CTEYQATCMNGEC | ||||||
Disulfide bond | 962↔980 | |||||
Sequence: CMNGECIDKSSICDGNPDC | ||||||
Disulfide bond | 974↔989 | |||||
Sequence: CDGNPDCSDASDEQSC | ||||||
Disulfide bond | 995↔1007 | |||||
Sequence: CQPNQFMCSNSKC | ||||||
Disulfide bond | 1002↔1020 | |||||
Sequence: CSNSKCVDRTWRCDGENDC | ||||||
Disulfide bond | 1014↔1029 | |||||
Sequence: CDGENDCGDNSDETSC | ||||||
Disulfide bond | 1038↔1050 | |||||
Sequence: CRYNEFQCRSGHC | ||||||
Disulfide bond | 1045↔1063 | |||||
Sequence: CRSGHCIPKSFQCDNVPDC | ||||||
Disulfide bond | 1057↔1072 | |||||
Sequence: CDNVPDCTDGTDEVGC | ||||||
Disulfide bond | 1477↔1486 | |||||
Sequence: CNEGYTGRRC | ||||||
Disulfide bond | 1820↔1829 | |||||
Sequence: CSDNTEGPSC | ||||||
Disulfide bond | 3445↔3462 | |||||
Sequence: CQNKGVCLESQTEQAYTC | ||||||
Disulfide bond | 3464↔3473 | |||||
Sequence: CQPGWTGRDC | ||||||
Disulfide bond | 3480↔3490 | |||||
Sequence: CTPGVCGAGRC | ||||||
Disulfide bond | 3501↔3510 | |||||
Sequence: CPLNRSGDRC | ||||||
Disulfide bond | 3754↔3763 | |||||
Sequence: CPFGFSGKHC | ||||||
Disulfide bond | 3925↔3952 | |||||
Sequence: CIVVVEGETVGQINLSSAAVNGVNANVC |
Keywords
- PTM
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 129-173 | Disordered | ||||
Sequence: NRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRW | ||||||
Region | 438-488 | Disordered | ||||
Sequence: AGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPE | ||||||
Compositional bias | 448-484 | Acidic residues | ||||
Sequence: PEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEP | ||||||
Domain | 851-938 | Ig-like | ||||
Sequence: PNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVN | ||||||
Domain | 1075-1164 | Ig-like | ||||
Sequence: PLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVT | ||||||
Domain | 1217-1395 | Laminin IV type A | ||||
Sequence: HRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEK | ||||||
Domain | 1451-1506 | Laminin EGF-like | ||||
Sequence: CPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRR | ||||||
Domain | 1585-1766 | Laminin IV type A | ||||
Sequence: RVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQ | ||||||
Domain | 1801-1850 | Laminin EGF-like | ||||
Sequence: CECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQP | ||||||
Domain | 1941-2116 | Laminin IV type A | ||||
Sequence: FILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIEL | ||||||
Domain | 2193-2284 | Ig-like | ||||
Sequence: PVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVS | ||||||
Domain | 2295-2377 | Ig-like | ||||
Sequence: PAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVI | ||||||
Domain | 2389-2480 | Ig-like | ||||
Sequence: PQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVN | ||||||
Domain | 2493-2575 | Ig-like | ||||
Sequence: PIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSID | ||||||
Domain | 2582-2669 | Ig-like | ||||
Sequence: PSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQ | ||||||
Domain | 2671-2758 | Ig-like | ||||
Sequence: PTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVE | ||||||
Compositional bias | 2761-2777 | Basic and acidic residues | ||||
Sequence: ERRGDIGGVDDDSDRDP | ||||||
Region | 2761-2795 | Disordered | ||||
Sequence: ERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGS | ||||||
Compositional bias | 2778-2795 | Polar residues | ||||
Sequence: INYNPPQQQNPGIHQPGS | ||||||
Domain | 2878-2962 | Ig-like | ||||
Sequence: PRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVA | ||||||
Domain | 2973-3059 | Ig-like | ||||
Sequence: PQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSID | ||||||
Domain | 3077-3170 | Ig-like | ||||
Sequence: PQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLE | ||||||
Domain | 3175-3257 | Ig-like | ||||
Sequence: PHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNIL | ||||||
Domain | 3263-3440 | Laminin G | ||||
Sequence: IPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPC | ||||||
Domain | 3436-3474 | EGF-like | ||||
Sequence: DCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCA | ||||||
Domain | 3476-3511 | EGF-like | ||||
Sequence: EGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQ | ||||||
Domain | 3520-3694 | Laminin G | ||||
Sequence: SLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSC | ||||||
Domain | 3728-3764 | EGF-like | ||||
Sequence: AMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQ | ||||||
Domain | 3770-3952 | Laminin G | ||||
Sequence: GFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVC |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length3,967
- Mass (Da)439,538
- Last updated2014-06-11 v2
- Checksum15BA8B136F0834B1
Computationally mapped potential isoform sequences
There are 22 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q9W4Y3 | Q9W4Y3_DROME | trol | 4479 | ||
A0A6H2EG25 | A0A6H2EG25_DROME | trol | 3972 | ||
Q8IRV7 | Q8IRV7_DROME | trol | 3105 | ||
Q8IRV8 | Q8IRV8_DROME | trol | 3887 | ||
Q8IRV9 | Q8IRV9_DROME | trol | 4007 | ||
E1JJC0 | E1JJC0_DROME | trol | 4411 | ||
X2JDK9 | X2JDK9_DROME | trol | 3805 | ||
M9NES6 | M9NES6_DROME | trol | 4451 | ||
M9NET2 | M9NET2_DROME | trol | 3897 | ||
X2JE09 | X2JE09_DROME | trol | 3973 | ||
M9NE56 | M9NE56_DROME | trol | 4176 | ||
M9NE61 | M9NE61_DROME | trol | 4150 | ||
M9NDL5 | M9NDL5_DROME | trol | 4434 | ||
M9NDM1 | M9NDM1_DROME | trol | 3806 | ||
M9NGK3 | M9NGK3_DROME | trol | 3728 | ||
Q9W4Y4 | Q9W4Y4_DROME | trol | 4150 | ||
X2JCE8 | X2JCE8_DROME | trol | 4203 | ||
M9NFR6 | M9NFR6_DROME | trol | 3833 | ||
M9NFS1 | M9NFS1_DROME | trol | 4299 | ||
Q7KVZ0 | Q7KVZ0_DROME | trol | 4178 | ||
X2JAC7 | X2JAC7_DROME | trol | 2853 | ||
A0A023GRW4 | A0A023GRW4_DROME | trol | 3989 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 448-484 | Acidic residues | ||||
Sequence: PEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEP | ||||||
Compositional bias | 2761-2777 | Basic and acidic residues | ||||
Sequence: ERRGDIGGVDDDSDRDP | ||||||
Compositional bias | 2778-2795 | Polar residues | ||||
Sequence: INYNPPQQQNPGIHQPGS |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE014298 EMBL· GenBank· DDBJ | AFH07211.2 EMBL· GenBank· DDBJ | Genomic DNA |