M7X3Z4 · M7X3Z4_RHOT1

Function

function

Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH.

Catalytic activity

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.

Features

Showing features for binding site, active site.

147650100150200250300350400450
Type
IDPosition(s)Description
Binding site90substrate; ligand shared between dimeric partners; in other chain
Binding site116-118substrate; ligand shared between dimeric partners; in other chain
Active site170Proton acceptor
Binding site173-174substrate; ligand shared between dimeric partners; in other chain
Active site177Proton donor
Binding site178substrate; ligand shared between dimeric partners; in other chain
Binding site247substrate; ligand shared between dimeric partners; in other chain
Binding site274substrate; ligand shared between dimeric partners; in other chain
Binding site433substrate; ligand shared between dimeric partners
Binding site439substrate; ligand shared between dimeric partners

GO annotations

AspectTerm
Molecular FunctionNADP binding
Molecular Functionphosphogluconate dehydrogenase (decarboxylating) activity
Biological ProcessD-gluconate metabolic process
Biological Processpentose-phosphate shunt

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    6-phosphogluconate dehydrogenase, decarboxylating
  • EC number

Gene names

    • ORF names
      RHTO_02788

Organism names

Accessions

  • Primary accession
    M7X3Z4

Proteomes

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain166-4636-phosphogluconate dehydrogenase C-terminal

Sequence similarities

Belongs to the 6-phosphogluconate dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    476
  • Mass (Da)
    52,470
  • Last updated
    2013-05-29 v1
  • MD5 Checksum
    73F74C6B641EA7F9CE833F2A8B39E4F5
MGQNLILNMADKGFTVCAYNRTVSKVDHFLENEAKGKSIVGAHSIEELCAKLKTPRKIVLLVKAGQAVDDFIAQLEPHLEKGDIVIDGGNSHFPDSNRRTKELESKGLLFVGSGVSGGEEGARYGPSLMPGGSTAAWPHIKEIFQKTAAQTDGEPCCDWVGEEGAGHYVKMVHNGIEYGDMQLITEAYDILKRGFGMHEKEIADIFERWNKGVLDSYLIEITTQILRYNDDDGTPLVTKILDAASQKGTGKWTATNALDLGMPVTLIGEAVFARCLSAIKDERVRASKVIGGPQIEPFSGDKKQFIDDLEQALYASKIVSYAQGFMLMREAAKTYGWHLNNAGIALMWRGGCIIRSVFLGDITKAYQKNPELENLLFDDFFNKAVHKAQPGWRRIVAQGALWGIPTPAFSTALSFFDGYRTERLPASLLQAQRDMFGAHTFRVLPQFANDKLKEGQDIHVNWTGRGGNVSASTYNV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KB722643
EMBL· GenBank· DDBJ
EMS25061.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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