M7WNT1 · M7WNT1_RHOT1
- ProteinCyanate hydratase
- Genecyn1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids158 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
Transcriptional coactivator that stimulates GCN4-dependent transcriptional activity by bridging the DNA-binding region of GCN4 and TBP (SPT15), thereby recruiting TBP to GCN4-bound promoters. Involved in induction of the ribosome quality control (RQC) pathway; a pathway that degrades nascent peptide chains during problematic translation. Required to prevent stalled ribosomes from frameshifting.
Catalytic activity
- cyanate + hydrogencarbonate + 3 H+ = NH4+ + 2 CO2
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 98 | ||||
Active site | 101 | ||||
Active site | 124 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | cyanate hydratase activity | |
Molecular Function | DNA binding | |
Biological Process | cyanate metabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCyanate hydratase
- EC number
- Short namesCyanase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Pucciniomycotina > Microbotryomycetes > Sporidiobolales > Sporidiobolaceae > Rhodotorula
Accessions
- Primary accessionM7WNT1
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 85-156 | Cyanate lyase C-terminal | |||
Sequence similarities
Belongs to the MBF1 family.
Belongs to the cyanase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length158
- Mass (Da)18,058
- Last updated2013-05-29 v1
- MD5 ChecksumAB215C932E1A0E0A61D9C45160E4AD9F
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KB722668 EMBL· GenBank· DDBJ | EMS19510.1 EMBL· GenBank· DDBJ | Genomic DNA |