M7WNT1 · M7WNT1_RHOT1

Function

function

Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
Transcriptional coactivator that stimulates GCN4-dependent transcriptional activity by bridging the DNA-binding region of GCN4 and TBP (SPT15), thereby recruiting TBP to GCN4-bound promoters. Involved in induction of the ribosome quality control (RQC) pathway; a pathway that degrades nascent peptide chains during problematic translation. Required to prevent stalled ribosomes from frameshifting.

Catalytic activity

Features

Showing features for active site.

115820406080100120140
TypeIDPosition(s)Description
Active site98
Active site101
Active site124

GO annotations

AspectTerm
Molecular Functioncyanate hydratase activity
Molecular FunctionDNA binding
Biological Processcyanate metabolic process

Keywords

  • Molecular function

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Cyanate hydratase
  • EC number
  • Short names
    Cyanase
  • Alternative names
    • Cyanate hydrolase
    • Cyanate lyase

Gene names

    • Name
      cyn1
    • ORF names
      RHTO_04284

Organism names

Accessions

  • Primary accession
    M7WNT1

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain85-156Cyanate lyase C-terminal

Sequence similarities

Belongs to the MBF1 family.
Belongs to the cyanase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    158
  • Mass (Da)
    18,058
  • Last updated
    2013-05-29 v1
  • MD5 Checksum
    AB215C932E1A0E0A61D9C45160E4AD9F
MASVVQSLADVNQQLFEAKKTKKLSFEQIAQRMGRDEVWVAALFYGQAKPTDEEVDKLIDVLGPWIDAKAMKRHFNPHFFPERGQLTPMPPTDPTLYRLYEIIGVYGYALKSVIHEKFGDGIMSAINFSAKVEKVQKNGADTVRITYEGKWLPYDFHC

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KB722668
EMBL· GenBank· DDBJ
EMS19510.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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