M7WKR4 · M7WKR4_RHOT1
- ProteinCTP synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids600 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
Catalytic activity
- UTP + L-glutamine + ATP + H2O = CTP + L-glutamate + ADP + phosphate + 2 H+
Pathway
Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 404 | Nucleophile | |||
Active site | 533 | ||||
Active site | 535 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoophidium | |
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | CTP synthase activity | |
Molecular Function | identical protein binding | |
Biological Process | 'de novo' CTP biosynthetic process | |
Biological Process | glutamine metabolic process | |
Biological Process | pyrimidine nucleobase biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCTP synthase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Pucciniomycotina > Microbotryomycetes > Sporidiobolales > Sporidiobolaceae > Rhodotorula
Accessions
- Primary accessionM7WKR4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 2-270 | CTP synthase N-terminal | |||
Domain | 315-551 | Glutamine amidotransferase | |||
Sequence similarities
Belongs to the CTP synthase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length600
- Mass (Da)66,527
- Last updated2013-05-29 v1
- Checksum48A246DC7532E527
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KB722657 EMBL· GenBank· DDBJ | EMS21077.1 EMBL· GenBank· DDBJ | Genomic DNA |