M7BTJ8 · M7BTJ8_CHEMY

Function

Catalytic activity

Cofactor

Cu cation (UniProtKB | Rhea| CHEBI:23378 )

Note: Contains 1 topaquinone per subunit.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site2520Proton acceptor
Active site2605Schiff-base intermediate with substrate; via topaquinone

GO annotations

AspectTerm
Cellular Componentplasma membrane
Cellular Componentproteasome activator complex
Molecular FunctionATP binding
Molecular Functioncopper ion binding
Molecular Functionhistone H2AS1 kinase activity
Molecular Functionprimary methylamine oxidase activity
Molecular Functionprotein serine kinase activity
Molecular Functionquinone binding
Biological Processamine metabolic process
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Amine oxidase
  • EC number

Gene names

    • ORF names
      UY3_02262

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Testudinata > Testudines > Cryptodira > Durocryptodira > Americhelydia > Chelonioidea > Cheloniidae > Chelonia

Accessions

  • Primary accession
    M7BTJ8

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue26052',4',5'-topaquinone

Post-translational modification

Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

Keywords

  • PTM
    • #TPQ

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, domain, compositional bias.

TypeIDPosition(s)Description
Region1-30Disordered
Domain43-301Protein kinase
Region422-456Disordered
Region639-659Disordered
Region713-756Disordered
Compositional bias741-756Polar residues
Region817-1015Disordered
Compositional bias914-976Polar residues
Compositional bias1094-1141Polar residues
Region1094-1142Disordered

Sequence similarities

Belongs to the copper/topaquinone oxidase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,900
  • Mass (Da)
    322,184
  • Last updated
    2013-05-29 v1
  • Checksum
    CC000B41E3AFB4A2
MQRQPAQVAPEQQARAGWSGAQREENEEIETRAVATSPDGRFLKSDMWTGRGSFKTVYKGLDTETTVEVAWCELQTRKLSKAERQRFSEEVEMLKGLQHPNIVRFYDSWKSAIKGQICIVLLSELMTSGTLKTYLKRFKEMKLKVLRCWSRQILKGLHFLHTRSPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDEAVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGRKPNSFYKVKVPELKEIIEGCIRMNKAERYTIQDLLEHSFFQEDTGVHVELAEEDDGVKSGLKLWLRMDDTKKLHGKYKDNNAIEFLFELHKDVAEEVAQEMVTLGFVCEADYKLVAKAVRDRVVAIKRKREKVKRAQDELLRQEQEKQPGILPLLEELKCPPVPTTPQPSPPTPGSGDSVFGGTFPPEPEEPEADQHQHFLYRHTSYSSTTSDCETDGYLSSSGFVDSPDLTHCHSGTFSTGDPFSQPAVQSESCFPVSIAVSSPTERLPSAPASEFSSPVDSYASDVASGLSDGCDGLSAGERNIGISDKSDRVVECQLQTYNNKMVTFKFDLDGDNPEEIAAVMVTNEFILQSEQDGFIHRIRDIIQRVETLLRKDGQGATRADGSPQPESLSPSAAINGLPAELQLQDLSRSVSSSSSLSGSPSAAAWSWPSFLTAPGLAPYQLPTSQSFSQTAVPGPQAGGSLLPTTPPRGGLGPLSTPRNSTAPTALPWSPATSPLFSLAEMVSLAMMSMAQTLLPSISSAVSPPGGPLASAPIPRPSALYLGPAHFTSPGPTGLVEPAPRCSGTQEPTSSRVTGGWGPALAPQGLERSGTRESPLSSVRAPAVDSGLVSPCSLKPSSHLIVSESPAPGTAKARLSPINEEAKPQILGRFQVTTSKDPANSPLGQPSQSDREQSGPEPWEGVAGTSSQPSVPSSSALEGSTSSDSDSVPDTPVQDPDELLAEEGTPVALADSDQEGPAEGGAESPQQAVVSPVWMSYARSLSYLSSDDTESEDEEIWEELQSLRQKHLSEVQTLQAVQKREIEELYFRMGKQAPPGIVSPAAMLSSRQRRLSKGSFNPSRRNSLQRLELSQPTGIMRRNSLSGSSTGSQEQRPSRGVSFAGDLSRMFFLISNLNLPHCNLRPLLLVLSSAITENSLDPSSLDPPFRFMIKHVEESYNSTEESRINNEQGEGNIWGALKAQMCDTFVLRLVSCIQLASKLSFHYNIINNNTVLKFLQSLDYSYTKQNLVESELAILKALRFQINVPTPFAYVELLLEVLGHNGCLLPMKQLHKMCMHLLDLTYLMRNIIYDTLLKISIENSTPSELQIAKFLSVKEDFMLLAVGVISTSAFILNPEYWNQVDSFRERITSEAEDLVANFFPKKLLELDGFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPNMKKRKLEDCEETFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLYISSPSLSPPFVFPVLTIQPQSKQADGSLSAGCCKAPGVKPASCEPQTLSTLQGKHSDQSLVFADLTPEEMVQVVRYLQSSLGVPLVDAYNANPSDNCIYYIDVQLPTKAEVLGFLDHGGRRPPRQALAVVYFGNQPDPNVTEYVVGPLPTPTTHQDITVQKYGGKLPYHRRPVLDFEYKLVAGFLRRTAFPTALTFLSQVLDYDGTNLVAMTTAPRGFQSGDRNTWFILFHNVSGFFLHPVGLEVLVDHSSLDISQWRVSKVFFNGQYYGDLLQLESEFKQGHVKVDPVKRAPPDGGFSSMQPRAAPRAPFPLQYEPHDGPRYSVQNNQVVSRAWSFAFGVNVNTGMRLFDIRFKGERIVYEISVQDAISVYGSNCPGGMSTRYMDGSFGIGRFTYPLVRGVDCPYSATYVDTHYLAQSPNPRINKNSICIFEENSGSPLRRHYSNLQSLYYGGLTNSALVLRSIATLGNYDYVWDFIFYENGAIEAKVHATGYMTSSFLYGDGLDYGNRVGDHTLGTIHTHSIHYKVDLDVGATIFALVCVLLTRGVKPASCEPQTLSTLQGKHSDQSLVFADLTPEEMVQVVRYLQSSLGVPLVDAYNANPSDNCIYYIDVQLPTKAEVLGFLDHGGRRPPRQALAVVYFGNQPDPNVTEYVVGPLPTPTTHQDITVQKYGGKLPYHRRPVLGKEYEQIEIFLRKEAFSTAPTFLSQVLDYDGTNFASLTSAPRGFQSGDRNTWFILFHNVSGFFLHPVGLEVLVDHSSLDVSQWRVSKVFFNGQYYRDLLQLEREFKQGHVKVDPVKRAPPDGGFSSMQPRAAPRAPFPLQYEPHGPRHSVQNNQVVSRAWSFAFGVNVNTGMRLFDIRFKGERIVYEISVQDAISVYGSNCPGGMSTRYMDGSFGIGRFTYPLVRGVDCPYSATYVDTRYLIETQTPEKHKNSICIFEENSGSPLRRHYSNLQSLYYGGLTNSALVLRSIATLGNYDYVWDFIFYENGAIEAKVHATGYMTSSFLYGDGLDYGNRVGDHTLGTIHTHSIHYKVDLDVGGTYNTLVAHDMAFESVQAPWSPEHQIQRPRLTKTVLDTEDKAAFRLHSNMPRYIYFAANSENKWGHQRGYRIQIVSFTGEHLPETSLMERAISWGRYKLAVTKRKEEEPTSSSIYNQNDPWTPTVAFADFINNESIVTEDLVAWITTGFLHIPHAEDIPNTVTVGNGVSILLRPYNYYDTDPSIYSPDGVFFSSEQDSSVCEVNHIACLSKTASCLPVLPPFTYDGFQNLTRL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias741-756Polar residues
Compositional bias914-976Polar residues
Compositional bias1094-1141Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KB509732
EMBL· GenBank· DDBJ
EMP40524.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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