M6G211 · M6G211_LEPIR

Function

function

Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site33S-methyl-5'-thioadenosine (UniProtKB | ChEBI)
Binding site64spermidine (UniProtKB | ChEBI)
Binding site88spermidine (UniProtKB | ChEBI)
Binding site108S-methyl-5'-thioadenosine (UniProtKB | ChEBI)
Binding site139-140S-methyl-5'-thioadenosine (UniProtKB | ChEBI)
Active site157Proton acceptor
Binding site157-160spermidine (UniProtKB | ChEBI)
Binding site164S-methyl-5'-thioadenosine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionspermidine synthase activity
Biological Processspermidine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Polyamine aminopropyltransferase
  • Alternative names
    • Putrescine aminopropyltransferase
      (PAPT
      )
    • Spermidine synthase
      (SPDS
      ; SPDSY
      ) (EC:2.5.1.16
      ) . EC:2.5.1.16 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      speE
    • ORF names
      LEP1GSC037_3538

Organism names

Accessions

  • Primary accession
    M6G211

Proteomes

Interaction

Subunit

Homodimer or homotetramer.

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-237PABS

Sequence similarities

Belongs to the spermidine/spermine synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    280
  • Mass (Da)
    31,957
  • Last updated
    2013-05-29 v1
  • Checksum
    1F67AA1877498657
MELWLDEALELKNGRALKIKVKEFLHSRTTPFQKIDVFESVGFGRMFTLDGVVMMTEADEFAYHEMIVHVPMMSHPNPEKVLVIGGGDGGTVREVLKHPSVKEVHLCEIDKGVIDVCYEYFPEIANAMKDPRVKHAYEDGAKYVKDYQNYFDCIMVDSSDPVGPAEVLFKRPFYETMANCLKEGGICTTQGESFYYHGSIIRELFNFIPEIFKHCGYYYTVVPTYPSGIIGFTYCSKGPDPYTVVPDPQRVPQGLKYYSAEMHKAAFVLPQFAQKHIVRK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AFLW02000254
EMBL· GenBank· DDBJ
EMM79033.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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