M4ZS55 · M4ZS55_9FLAO

Function

function

Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Activity regulation

Feedback inhibited by histidine.

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionATP phosphoribosyltransferase activity
Molecular Functionmagnesium ion binding
Biological ProcessL-histidine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP phosphoribosyltransferase
  • EC number
  • Short names
    ATP-PRT
    ; ATP-PRTase

Gene names

    • Name
      hisG
    • ORF names
      BPAA_210

Organism names

  • Taxonomic identifier
  • Strain
    • BPAA
  • Taxonomic lineage
    Bacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Blattabacteriaceae > Blattabacterium

Accessions

  • Primary accession
    M4ZS55

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain51-205ATP phosphoribosyltransferase catalytic
Domain210-282Histidine biosynthesis HisG C-terminal

Sequence similarities

Belongs to the ATP phosphoribosyltransferase family. Long subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    285
  • Mass (Da)
    31,879
  • Last updated
    2013-05-29 v1
  • Checksum
    8F30598A530229DF
MNKLKIAIQKSGRLYEDSIKLLKDCSIEINIGIDKLKTTALNFPLEILFLRDDDIPQYLEDGVADIGIVGKNLLLEKRKRIKIKETLGFGKCRLSIAVPKSLSYNKIQDLDGKRIATSYPFLVREFFKKRYINAEIHEISGAVEIAPGIGLADCICDLVSSGSTLFMNGLKEVETVLQSEAVLASHLHLDSTQNIIMEKFLFRIRAVKKAKNNKYILLNVSNEKLEKIISYLPGIKSPVILPLANSECSSVHSVVNENDFWGIIENLKALGAQDILVLPIEKIIL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP012548
EMBL· GenBank· DDBJ
BAM99507.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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