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M3VX94 · M3VX94_FELCA

Function

Catalytic activity

Features

Showing features for binding site, active site, site.

1902100200300400500600700800900
Type
IDPosition(s)Description
Binding site88-90(6R)-10-formyltetrahydrofolate (UniProtKB | ChEBI)
Active site106Proton donor
Binding site142(6R)-10-formyltetrahydrofolate (UniProtKB | ChEBI)
Site142Essential for catalytic activity
Binding site571-573NADP+ (UniProtKB | ChEBI)
Binding site597-600NADP+ (UniProtKB | ChEBI)
Binding site630-635NADP+ (UniProtKB | ChEBI)
Binding site650-651NADP+ (UniProtKB | ChEBI)
Active site673
Active site673Proton acceptor
Active site707Proton donor
Binding site757NADP+ (UniProtKB | ChEBI)
Binding site804-806NADP+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionformyltetrahydrofolate dehydrogenase activity
Molecular Functionoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Biological Process10-formyltetrahydrofolate catabolic process
Biological Processbiosynthetic process
Biological Processone-carbon metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    10-formyltetrahydrofolate dehydrogenase
  • EC number

Gene names

    • Name
      ALDH1L1

Organism names

  • Taxonomic identifier
  • Strain
    • Abyssinian
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Feliformia > Felidae > Felinae > Felis

Accessions

  • Primary accession
    M3VX94

Proteomes

Subcellular Location

Keywords

PTM/Processing

Keywords

Proteomic databases

Expression

Gene expression databases

Interaction

Subunit

Homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain318-395Carrier

Sequence similarities

Belongs to the aldehyde dehydrogenase family.
In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
In the N-terminal section; belongs to the GART family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    902
  • Mass (Da)
    98,839
  • Last updated
    2019-12-11 v4
  • MD5 Checksum
    9F80462A2EE24F1FB9B029383210DF49
MKIAVIGQSLFGQEVYCHLRKEGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKIPRWRVKGQALPDVVAKYQALGAELNVLPFCSQFIPMEVINAPCHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTIFWADDGLDTGDLLLQKECEILPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGKAPRLPQPEEGATYEGIQKKETAKINWEQSAEAIHNWIRGNDKVPGAWTEACGQKLTFFNSTLNTAGLVPEGEALPIPGAHQPGIVTKAGLILFGNDDRMLLVKNIQLEDGRMIPASRFFSGADSSVLELTEAELVMAETVRSAWKRILPSVLEVEDSTDFFKSGAASVDVVRLVEEVKELCDGLELENEDVYMATTFGDFIQLLVKKLRGDNKESECIIDYVEKVVNKLTLRMPHQLFIGGLFVDAEGAKTYETINPTDGSVICQVSLAQVSDVDKAVAAAKDAFENGLWGKISARDRGRLLYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLTLTRKEPIGVCGIVIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCALSNVKKVSLELGGKSPLIIFADCDLSKAVQMGMSSVFFNKGENCIAAGRLFIEDSIHDHFVQKVVEEVKRMKIGNPLDRDTNHGPQNHQAHLRKLIEYCQRGVEEGATLVCGGSQVPRPGFFFEPTVFTDVEDHMFIAKEESFGPIMIISRFADGDVDTVLSRANATEFGLASGVFTRDINKALYVSDKLGAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEEALNEYLRVKTITFEY

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A337RUT4A0A337RUT4_FELCAALDH1L1907

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AANG04002863
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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