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M3VWP3 · M3VWP3_FELCA

Function

Catalytic activity

Features

Showing features for binding site, active site, site.

1923100200300400500600700800900
Type
IDPosition(s)Description
Binding site110-112(6R)-10-formyltetrahydrofolate (UniProtKB | ChEBI)
Active site128Proton donor
Binding site164(6R)-10-formyltetrahydrofolate (UniProtKB | ChEBI)
Site164Essential for catalytic activity
Binding site592-594NADP+ (UniProtKB | ChEBI)
Binding site618-621NADP+ (UniProtKB | ChEBI)
Binding site651-656NADP+ (UniProtKB | ChEBI)
Binding site671-672NADP+ (UniProtKB | ChEBI)
Active site694
Active site694Proton acceptor
Active site728Proton donor
Binding site778NADP+ (UniProtKB | ChEBI)
Binding site825-827NADP+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrion
Cellular Componentnucleoplasm
Molecular Functionaldehyde dehydrogenase (NAD+) activity
Molecular Functionformyltetrahydrofolate dehydrogenase activity
Biological Process10-formyltetrahydrofolate catabolic process
Biological Processbiosynthetic process
Biological Processfatty acid beta-oxidation
Biological Processfolic acid metabolic process
Biological ProcessNADPH regeneration
Biological Processone-carbon metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    10-formyltetrahydrofolate dehydrogenase
  • EC number

Gene names

    • Name
      ALDH1L2

Organism names

  • Taxonomic identifier
  • Strain
    • Abyssinian
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Feliformia > Felidae > Felinae > Felis

Accessions

  • Primary accession
    M3VWP3

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Keywords

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain339-416Carrier

Sequence similarities

Belongs to the aldehyde dehydrogenase family.
In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
In the N-terminal section; belongs to the GART family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    923
  • Mass (Da)
    101,646
  • Last updated
    2018-10-10 v3
  • MD5 Checksum
    23821B5C2ECF0F6B908E1422D2B8B625
MLWLGSQALRRFSTGRAHFKNKLKLALIGQSLFGQEVYSHLRKEGHRVVGVFTVPDKDGKTDPLALAAEKDGTPVFKFPRWRVKGKTIKEVAEAYKSVGAELNVLPFCTQFIPMDVIDSPKYGSIIYHPSILPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQKSCDVEPNDTVDALYNRFLFPEGIKAMVEAVQLIADGKAPRIPQPEEGATYEGIQKKENAEISWDQSAEVLHNWIRGHDKVPGAWTEINGQMVTFYGSSLLKSSVPSGEPLEIKGATKPGLVTKNGLVLFGNDGKALMVRNLQFEDGRMIPASQYFSAGETSVLELTAEEVKVAGTIKVIWAGILSNVPVIEDSTDFFKSGASSMDVVRLVEEIRQKCGGLQLQNEDVYLATKFEDFIQKVVRKLRGEESEEELVVDYVSKEVNEMTVKMPYQCFINGQFTDADDGKTYDTINPTDGSIICKVSYASLVDVDKAVAAAKDAFENGEWGRMNARERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTAIGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEEAIHDEFVTRVVEEIKKMKIGDPLDRSTDHGPQNHKAHLEKLLQYCEAGVKEGATLVYGGRQVQRPGFFMEPTVFTDVEDHMYLAKEESFGPIMVISKFQNGDIDGVLQRANNTEYGLASGVFTRDINKAMYVSEKLEAGTVFVNTYNKTDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTLEY

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AANG04003655
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

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