M3FEV6 · M3FEV6_9ACTN

Function

function

Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

Catalytic activity

Activity regulation

Inhibited by fructose 1,6-bisphosphate (FBP).

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.

Features

Showing features for binding site.

151950100150200250300350400450500
TypeIDPosition(s)Description
Binding site25ADP (UniProtKB | ChEBI)
Binding site25ATP (UniProtKB | ChEBI)
Binding site25sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site26ATP (UniProtKB | ChEBI)
Binding site27ATP (UniProtKB | ChEBI)
Binding site29ADP (UniProtKB | ChEBI)
Binding site95glycerol (UniProtKB | ChEBI)
Binding site95sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site96glycerol (UniProtKB | ChEBI)
Binding site96sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site147glycerol (UniProtKB | ChEBI)
Binding site147sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site262glycerol (UniProtKB | ChEBI)
Binding site262sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site263glycerol (UniProtKB | ChEBI)
Binding site284ADP (UniProtKB | ChEBI)
Binding site284ATP (UniProtKB | ChEBI)
Binding site328ADP (UniProtKB | ChEBI)
Binding site328ATP (UniProtKB | ChEBI)
Binding site332ATP (UniProtKB | ChEBI)
Binding site429ADP (UniProtKB | ChEBI)
Binding site429ATP (UniProtKB | ChEBI)
Binding site433ADP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionglycerol kinase activity
Biological Processglycerol catabolic process
Biological Processglycerol-3-phosphate metabolic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol kinase
  • EC number
  • Alternative names
    • ATP:glycerol 3-phosphotransferase
    • Glycerokinase
      (GK
      )

Gene names

    • Name
      glpK
    • ORF names
      SBD_7105

Organism names

Accessions

  • Primary accession
    M3FEV6

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain18-269Carbohydrate kinase FGGY N-terminal
Domain279-468Carbohydrate kinase FGGY C-terminal

Sequence similarities

Belongs to the FGGY kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    519
  • Mass (Da)
    56,890
  • Last updated
    2013-05-01 v1
  • Checksum
    FC759F7D088B2CB7
MNFQEHTVTDAHTAGPFIAAIDQGTTSSRCIVFDRDGRIVSVDQKEHEQIFPKPGWVEHDATEIWTNVQEVVAGAIEKAGITRDDIKAIGITNQRETTLLWDKNTGEPVHNAIVWQDTRTDALCRELGRNVGQDRFRRETGLPLASYFAGPKARWLLDNVEGLRERAEAGDILFGTMDSWVIWNLTGGVDGGKHYTDVTNASRTMLMNLHTLEWDDKIAESIGVPLSMLPEIRSSAEVYGEVAGGRLGDLLGGIPVASALGDQQAALFGQTCFEEGEAKSTYGTGTFMLLNTGEKIINSYSGLLTTVGYRIGDQKPVYALEGSIAVTGSLVQWMRDQMGLISTAAEIETLALSVEDNGGAYFVPAFSGLFAPYWRSDARGVIAGLTRYVTKAHLARAVLEATAWQTREITDAMTKDSGVELAALKVDGGMTSNNLLMQTLSDFLDAPVVRPMVAETTCLGAAYAAGLAVGFWNSTDDLRANWRRAAEWTPRMDAETRDREYKSWLKAVERTMGWLEDES

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KB405096
EMBL· GenBank· DDBJ
EMF51400.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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