M3E731 · M3E731_9ACTN

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

Type
IDPosition(s)Description
Site105Transition state stabilizer
Active site109Proton acceptor
Binding site272Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processcellular response to hydrogen peroxide
Biological Processhydrogen peroxide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • ORF names
      SBD_6438

Organism names

Accessions

  • Primary accession
    M3E731

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for cross-link.

TypeIDPosition(s)Description
Cross-link231↔257Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-108)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region1-37Disordered
Domain142-429Plant heme peroxidase family profile
Region276-296Disordered

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    738
  • Mass (Da)
    80,206
  • Last updated
    2013-05-01 v1
  • Checksum
    F4F4576918E01FBD
MTENHDAIVTDAKPEETGGCPVAHGRAAHPTQGGGNRQWWPERLNLKILAKDPVVANPLGGEFDYAEAFNNLDLAAVKQDIAEVLTTSQDWWPADFGNYGPLMIRMAWHSAGTYRISDGRGGGGRGQQRFAPLNSWPDNGNLDKARRLLWPVKKKYGQSISWADLMILTGNVALEQMGFETFGFAGGRADVWEADEDVYWGPETTWLDDQRYTGDRELENPLGAVQMGLIYVNPEGPNGNPDPLAAARDIRETFRRMAMNDEETVALIAGGHTFGKTHGAGPADNVGDDPEAASMEEQGLGWKSTYGTGKGGDAITSGLEVTWTETPTQWSNNFFKNLFEYEYELTQSPAGANQWVAKNAEAIIPDAHDASKTKLPTMLTTDLSLRFDPIYAEISRRFYEHPDQFADAFARAWFKLTHRDMGPKSLYLGPEVPAETLLWQDPLPQAEGPVIDAADIAALKTKLLASGLTVSQLVSTAWASASTFRASDKRGGANGARIRLEPQRGWEVNNPEDLRHVLSVLEGVQAEFNAGAKKVSLADLIVLGGAAAVEKAAKDAGFDVVVPFTPGRVDATEEHTDAESFAALEPAADGFRNYQGKGNRLPAEYLLLDRANLLSLSAPELTVLVGGLRVLGANHAGSTHGVFTGTPGVLTNDFFVNLLDLGTTWKSTSADQTLFEGRDADTGEVKWTGTRADLVFGSNSELRALAEVYASDDAKEKFVKDFVAAWAKVADLDRFDLV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KB405095
EMBL· GenBank· DDBJ
EMF51916.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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