M2WKU2 · M2WKU2_DOTSN
- ProteinAurora kinase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids906 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 67 | ATP (UniProtKB | ChEBI) | |||
Binding site | 75 | ATP (UniProtKB | ChEBI) | |||
Active site | 158 | Proton acceptor | |||
Binding site | 162-163 | ATP (UniProtKB | ChEBI) | |||
Binding site | 176 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chromosome passenger complex | |
Cellular Component | spindle microtubule | |
Cellular Component | spindle midzone | |
Molecular Function | ATP binding | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | mitotic spindle organization | |
Biological Process | protein phosphorylation | |
Biological Process | regulation of cytokinesis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAurora kinase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Dothideomycetes > Dothideomycetidae > Mycosphaerellales > Mycosphaerellaceae > Dothistroma
Accessions
- Primary accessionM2WKU2
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for cross-link.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Cross-link | 160 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) | |||
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 41-288 | Protein kinase | |||
Region | 387-518 | Disordered | |||
Compositional bias | 389-412 | Basic and acidic residues | |||
Compositional bias | 413-443 | Polar residues | |||
Compositional bias | 473-501 | Polar residues | |||
Compositional bias | 538-555 | Basic and acidic residues | |||
Region | 538-817 | Disordered | |||
Compositional bias | 576-715 | Polar residues | |||
Compositional bias | 772-794 | Polar residues | |||
Compositional bias | 799-817 | Acidic residues | |||
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length906
- Mass (Da)100,379
- Last updated2013-05-01 v1
- ChecksumE7768052B658D72F
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 389-412 | Basic and acidic residues | |||
Compositional bias | 413-443 | Polar residues | |||
Compositional bias | 473-501 | Polar residues | |||
Compositional bias | 538-555 | Basic and acidic residues | |||
Compositional bias | 576-715 | Polar residues | |||
Compositional bias | 772-794 | Polar residues | |||
Compositional bias | 799-817 | Acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KB446545 EMBL· GenBank· DDBJ | EME39598.1 EMBL· GenBank· DDBJ | Genomic DNA |