M2SNN6 · LAEA_COCH5
- ProteinSecondary metabolism regulator LAE1
- GeneLAE1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids307 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Methyltransferase that performs automethylation (By similarity).
No other methyl-accepting substrate has been identified yet (By similarity).
Component of the velvet transcription factor complex that acts as a global regulator for secondary metabolite gene expression (By similarity).
Controls the expression of the T-toxin gene cluster (PubMed:22383877).
Promotes oxidative stress tolerance and acts as a virulence factors during infection (PubMed:22383877).
Negatively regulate mycelial pigmentation and controls sexual development, as well as asexual development during vegetative growth (PubMed:22383877).
No other methyl-accepting substrate has been identified yet (By similarity).
Component of the velvet transcription factor complex that acts as a global regulator for secondary metabolite gene expression (By similarity).
Controls the expression of the T-toxin gene cluster (PubMed:22383877).
Promotes oxidative stress tolerance and acts as a virulence factors during infection (PubMed:22383877).
Negatively regulate mycelial pigmentation and controls sexual development, as well as asexual development during vegetative growth (PubMed:22383877).
Catalytic activity
- L-methionyl-[protein] + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + S-methyl-L-methionyl-[protein]This reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | methyltransferase activity | |
Biological Process | methylation | |
Biological Process | sporulation resulting in formation of a cellular spore |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameSecondary metabolism regulator LAE1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Dothideomycetes > Pleosporomycetidae > Pleosporales > Pleosporineae > Pleosporaceae > Bipolaris
Accessions
- Primary accessionM2SNN6
- Secondary accessions
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000435748 | 1-307 | Secondary metabolism regulator LAE1 | |||
Sequence: MTSNGLPVPAQNSNYMENGRWYHGFRRGLYMYPCDEPEKDRMDIYHQFFAVARRGQLHQAPVPSEPHLQPRILDVGCGTGIWAIDMADKYLNAEVLGLDLVNIQPEKIPPNLRFRVPRDYESPWTLGEDSWDLIHLRMACGSVESWPELYQKIYTHLKPGTGWIEHIEIDMEPRCDDYTLPPDSMLRKWYGWLADATQRAYRPIAYEHRTRQLLQAAGFIDIQETVIRVPYNTWPNDPHQKDIGRWYNLGLTEGLEALTFAPLTRVYHWDLNAHVRPIVEGVRRELCNRKIHAYNNIHIWTARRPQQ |
Interaction
Subunit
Component of the heterotrimeric velvet complex composed of LAE1, VEL1 and VEL2; VEL1 acting as a bridging protein between LAE1 and VEL2 (By similarity).
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length307
- Mass (Da)36,056
- Last updated2013-05-01 v1
- ChecksumBD0188BF582D9870
Sequence caution
Keywords
- Technical term