M1ZMM0 · M1ZMM0_DANRE

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FAD (UniProtKB | Rhea| CHEBI:57692 )

Mo-molybdopterin (UniProtKB | Rhea| CHEBI:71302 )

Note: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
[2Fe-2S] cluster (UniProtKB | Rhea| CHEBI:190135 )

[2Fe-2S] cluster (UniProtKB | Rhea| CHEBI:190135 )

Note: Binds 2 [2Fe-2S] clusters.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site47[2Fe-2S] cluster 1 (UniProtKB | ChEBI)
Binding site52[2Fe-2S] cluster 1 (UniProtKB | ChEBI)
Binding site55[2Fe-2S] cluster 1 (UniProtKB | ChEBI)
Binding site77[2Fe-2S] cluster 1 (UniProtKB | ChEBI)
Binding site117[2Fe-2S] cluster 2 (UniProtKB | ChEBI)
Binding site120[2Fe-2S] cluster 2 (UniProtKB | ChEBI)
Binding site152[2Fe-2S] cluster 2 (UniProtKB | ChEBI)
Binding site154[2Fe-2S] cluster 2 (UniProtKB | ChEBI)
Binding site262-269FAD (UniProtKB | ChEBI)
Binding site365FAD (UniProtKB | ChEBI)
Binding site409FAD (UniProtKB | ChEBI)
Binding site427FAD (UniProtKB | ChEBI)
Binding site773Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI)
Binding site804Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI)
Binding site918Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI)
Binding site920substrate
Binding site1086Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI)
Active site1268Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentperoxisome
Molecular Function2 iron, 2 sulfur cluster binding
Molecular Functionaldehyde oxidase activity
Molecular FunctionFAD binding
Molecular Functioniron ion binding
Molecular Functionxanthine dehydrogenase activity
Molecular Functionxanthine oxidase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    xanthine dehydrogenase
  • EC number

Gene names

    • Name
      aox5
    • Synonyms
      aox3
      , etID47878.22
      , fc18g02
      , wu:fc18g02
      , xdh

Organism names

  • Taxonomic identifier
  • Strain
    • Tuebingen
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    M1ZMM0
  • Secondary accessions
    • A0A8M1P013

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain8-952Fe-2S ferredoxin-type
Domain234-419FAD-binding PCMH-type

Sequence similarities

Belongs to the xanthine dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,336
  • Mass (Da)
    147,202
  • Last updated
    2013-05-01 v1
  • Checksum
    85C1AA5B7EA8EE94
MSSLSVNSELVFYINGKKIVEKNADPEEMLLAYLRRKVGLTGAKYGCGGGGCGACTVMVSRYDPLQDTVLHWSVNACLQPICSLHGAAVVTVEGIGSTKTKLHPVQERIVKAHGSQCGFCTPGMVMSMYTLLRNNPHPTIEDIRETLGGNLCRCTGYRPIIDGFKTFCETPVCCQNGGGNGKCCMENGNSHNESDISGELFIMDNVLPLDPTQDLIFPPELLIMGKKKAERHCFQGEKVRWISPSDLKDLIKLKAEHSDAPLLVGNTTIGPKMNLNKTVHPLVIYGGSIAELQAIKWRKNCITVGAGCSLSVLKDVLQQRIEDLGPEKSRVYQALVQTLQCLAGKQIRNMATIGGNILSANPKYDLSSILAAAECTLHIASKDGDREICLSEEFFTDFGKTALRPEEILLAIDIPHSKPWEFVSAFRQAQRREFAFSIVNAGMRVAFRHDSNVVEHLDIFYGGVGCTLVKARHTCKELIGRKWDEKLLAEGTQLLEEEISVPATVPGGREEYRKALVLSFFFKFYMQVLLELQQREVGVNDLPLEYLSALKPFKNEVPQGNYSYQLVPETQSSSDPVGRPNVHLAALQQATGEAVYYDDIPSVKGELFVSMVTSTRAHAKIISIDASVALAMPGVVDFISAKDVPGQNRRLWFNNPEELFAEEEVICVGQIIGAIVAETREQAKRAAQQVDITYQDMQPVFFTIEEAIEHESFFDPKRKLERGNVEEGFAKADQILEGEMYMGGQEHFYMETQGVIAIPTGEASEIELYVASQHAAYTQEVVGITLGIDSNKITCHVKRLGGGFGGKVMKIASLSAIAATAAIKTGHAVRCVLERGDDMLITSGRSPFLGRYKIGYMNDGTILAADITYYSNGGCTLDESSFIMEKALLHMDNGYKIPNLRGRGLVCKTFLPSYTAFRGFGGPQGLTIIESVLHEVAVKCGLPAHQVRDINLYKEEKCFTHHKQLFSPHDMVRCWNECLEKSNYTQRCQYIEQFNGHNHWKKRGISIVPIKFGIGFSKGFYNQGAALVNVYKDGSVVISHGGTEMGQGINTKAIQIASRILKVSMSSIHIKETCTGNVPNAAPSAASFGTDAVGMAVKNGCEKLMRRLEPLIKKHPQYTWQQLVVEAYCQKISLSATGFFMGPHTSVDWEKSEGNAYYYFTFGACCSEVEIDCLTGDHKNIRTDIVMDVGRSINPALDVGQVEGGFVQGIGLYTIEELQFSPQGVLLTRGPSQYKIPALCDVPPQINVHLLRNADNPHAIYSSKGIGEPPVFFGCTLFFAIKEAIAAARKERGLSESFSFSSPATAEKIRMACEDCFTRMIPQDKKVKTKPWAINV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX649296
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
BK008657
EMBL· GenBank· DDBJ
DAA64406.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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