M1VNU0 · M1VNU0_STRSU

  • Protein
    3-phosphoshikimate 1-carboxyvinyltransferase
  • Gene
    aroA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site203-phosphoshikimate (UniProtKB | ChEBI)
Binding site20phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site213-phosphoshikimate (UniProtKB | ChEBI)
Binding site253-phosphoshikimate (UniProtKB | ChEBI)
Binding site92phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site120phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site1663-phosphoshikimate (UniProtKB | ChEBI)
Binding site1683-phosphoshikimate (UniProtKB | ChEBI)
Binding site168phosphoenolpyruvate (UniProtKB | ChEBI)
Active site312Proton acceptor
Binding site3123-phosphoshikimate (UniProtKB | ChEBI)
Binding site3393-phosphoshikimate (UniProtKB | ChEBI)
Binding site343phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site385phosphoenolpyruvate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function3-phosphoshikimate 1-carboxyvinyltransferase activity
Biological Processamino acid biosynthetic process
Biological Processaromatic amino acid family biosynthetic process
Biological Processchorismate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-phosphoshikimate 1-carboxyvinyltransferase
  • EC number
  • Alternative names
    • 5-enolpyruvylshikimate-3-phosphate synthase
      (EPSP synthase
      ; EPSPS
      )

Gene names

    • Name
      aroA

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 2524
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus

Accessions

  • Primary accession
    M1VNU0

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Sequence similarities

Belongs to the EPSP synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    426
  • Mass (Da)
    45,970
  • Last updated
    2013-05-01 v1
  • Checksum
    C4285D2700D74EFD
MKLRRNVEKLKGTIRVPGDKSISHRSIIFGSLAKGVTRVHDILRGEDVLSTMQVFRDLGVKIEDNGDIVEVHGVGFDGLQAPKNDLDMGNSGTSIRLISGVLAGQDFEATMFGDDSLSKRPMDRVTIPLSQMGVEISGQTERDLPPLTIKGNKNLKPIRYQLPVASAQVKSALIFAALQAEGESVIVEKELTRNHTEDMIVQFGGQLEVNGKEIRIQGGQEFIAQEITVPGDISSAAFWLVAGLIVPGSKIVLENVGINETRTGILDVIKAMGGKMTLSNIDELAKSATITVETSELKATEIAGELIPRLIDELPIITLLATQAHGTTIIRDAEELKVKETDRIQVVADALNSMGATIEPTEDGMIIHGPTALHGAEINTFGDHRIGMMTAIAALLAKDGEVVLERAEAINTSYPAFFEHLNSLMD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB737818
EMBL· GenBank· DDBJ
BAM94567.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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