M1VKJ0 · M1VKJ0_CYAM1

Function

Catalytic activity

  • ATP-dependent breakage, passage and rejoining of double-stranded DNA.
    EC:5.6.2.2 (UniProtKB | ENZYME | Rhea)

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchloroplast
Cellular Componentnuclear chromosome
Molecular FunctionATP binding
Molecular FunctionDNA binding
Molecular FunctionDNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
Molecular Functionidentical protein binding
Molecular Functionmetal ion binding
Biological ProcessDNA topological change
Biological Processepidermal cell fate specification
Biological Processmeiotic DNA double-strand break formation
Biological Processmeiotic DNA double-strand break processing
Biological Processreciprocal meiotic recombination

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA topoisomerase (ATP-hydrolyzing)
  • EC number

Gene names

    • ORF names
      CYME_CMQ111C

Organism names

Accessions

  • Primary accession
    M1VKJ0

Proteomes

Genome annotation databases

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, coiled coil, domain.

Type
IDPosition(s)Description
Region1-34Disordered
Compositional bias14-30Polar residues
Coiled coil39-66
Domain147-208Spo11/DNA topoisomerase VI subunit A N-terminal
Domain257-427Topoisomerase 6 subunit A/Spo11 TOPRIM

Sequence similarities

Belongs to the TOP6A family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    433
  • Mass (Da)
    48,924
  • Last updated
    2013-05-01 v1
  • Checksum
    F96D5268ABC9D0B8
MVAKRKKTATEPRLSTASRKWKQAAESGAVSSGTAAVDAESFLNRVRELKREIESREAAKQRFILQQSSDASSAARIEVRELDCDQVLAELERVILSAAKSILEGRGLSYKVPRRSAGNQEYVEELERIVLKDGVAIRNFASVASVRKTTIMTRVLQLVHELCTRRIHTTKRDLFYTDVKLFRQQTESDDVLNDVACLIGCTRNSLNVVASEKGIVVGRVTFQEDGDLIDCTRMGVGGKAIPPYTDRITNITSDAEFILLVEKDAAFMRLAEDRFYNRVKCIIVTAKGQPDVGTRLFLRRLKRELHLPILGLVDSDPYGLKILSVYMSGSKGMSYDSANLATPDIKWLGIRPTDLDRYGIPEQCRLAMTENDLKTGKDMLEEDFIKKNPAWHRELSLMVKRKEKAEIQALSNFGFQYLTEVYLPEKIRHGDWI

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias14-30Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP006499
EMBL· GenBank· DDBJ
BAM82023.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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