M0R7E7 · M0R7E7_RAT

  • Protein
    mitogen-activated protein kinase kinase
  • Gene
    Map2k3
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    5/5

Function

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site165ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular FunctionMAP kinase kinase activity
Molecular Functionprotein kinase binding
Molecular Functionprotein serine/threonine kinase activity
Molecular Functionprotein tyrosine kinase activity
Biological Processcardiac muscle contraction
Biological Processcellular response to lipopolysaccharide
Biological Processcellular response to sorbitol
Biological Processcellular response to vascular endothelial growth factor stimulus
Biological Processheart development
Biological Processinflammatory response
Biological ProcessMAPK cascade
Biological Processnegative regulation of hippo signaling
Biological Processp38MAPK cascade
Biological Processpositive regulation of blood vessel endothelial cell migration
Biological Processpositive regulation of DNA-templated transcription
Biological Processpositive regulation of MAPK cascade
Biological Processpositive regulation of nitric-oxide synthase biosynthetic process
Biological Processpositive regulation of protein phosphorylation
Biological Processregulation of cytokine production
Biological Processresponse to ischemia
Biological Processstress-activated protein kinase signaling cascade

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    mitogen-activated protein kinase kinase
  • EC number

Gene names

    • Name
      Map2k3

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    M0R7E7

Proteomes

Organism-specific databases

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias70-86Polar residues
Region70-119Disordered
Domain136-397Protein kinase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    419
  • Mass (Da)
    47,091
  • Last updated
    2022-05-25 v1
  • Checksum
    97A9E1B24ED4BD75
MGGAYVAPSVGVRRCPVWLWRRPPRTLGTVASVSPVAHRLPPLPATSNHERARPRCSLLSSRLVLSSATVRSMESPAASPPASLPQTKGKSKRKRDLRISCVSKPPVSNPTPPRNLDSRTFITIGDRNFEVEADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLEKNMKIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADQFSPEFVDFTSQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
F7EXM7F7EXM7_RATMap2k3340

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias70-86Polar residues

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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