M0FRC5 · M0FRC5_9EURY
- ProteinDNA polymerase II small subunit
- GenepolB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids533 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.
Catalytic activity
- a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | DNA binding | |
Molecular Function | DNA-directed DNA polymerase activity | |
Molecular Function | single-stranded DNA 3'-5' DNA exonuclease activity | |
Biological Process | DNA catabolic process | |
Biological Process | DNA-templated DNA replication |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA polymerase II small subunit
- EC number
- Short namesPol II
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Halobacteria > Halobacteriales > Haloferacaceae > Haloferax
Accessions
- Primary accessionM0FRC5
Proteomes
Interaction
Subunit
Heterodimer of a large subunit and a small subunit.
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 65-130 | Disordered | ||||
Sequence: PAADPSGTEPTPPAAADAANAADADPAASAASDPSVSAATSHDNAAHTDQSVPAEAQGTSGGRNVD | ||||||
Compositional bias | 97-122 | Polar residues | ||||
Sequence: DPSVSAATSHDNAAHTDQSVPAEAQG | ||||||
Domain | 281-478 | DNA polymerase alpha/delta/epsilon subunit B | ||||
Sequence: ALISDVHVGSQEFMADAWNRFADWLHTEEAARIEYLLIAGDMVEGVGVYPNQDEELDVIDIYEQYEAFSEHLKSVPGDLEIVMIPGNHDAVRLAEPQPGFDDELRDIMSAHDARITSNPSMVTLEGVNVLMYHGVSLDEVIAELPADKASYDEPHKAMYQLLKKRHVAPQFGGHTRLAPEELDYLVMEDVPDIFHTGH |
Sequence similarities
Belongs to the DNA polymerase delta/II small subunit family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length533
- Mass (Da)57,850
- Last updated2013-04-03 v1
- Checksum809B6DA9188B9B03
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 97-122 | Polar residues | ||||
Sequence: DPSVSAATSHDNAAHTDQSVPAEAQG |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AOLE01000025 EMBL· GenBank· DDBJ | ELZ62596.1 EMBL· GenBank· DDBJ | Genomic DNA |