M0EF87 · M0EF87_9EURY

Function

function

Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis.
Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (Thermus route): step 2/5.

Features

Showing features for site, binding site.

Type
IDPosition(s)Description
Site18Transition state stabilizer
Binding site77substrate
Binding site185substrate
Site246Transition state stabilizer

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionacetylglutamate kinase activity
Molecular FunctionATP binding
Molecular FunctionN2-acetyl-L-aminoadipate kinase activity
Biological Processarginine biosynthetic process via ornithine
Biological ProcessL-arginine biosynthetic process
Biological Processlysine biosynthetic process via aminoadipic acid

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative [LysW]-aminoadipate/[LysW]-glutamate kinase
  • EC number

Gene names

    • Name
      lysZ
    • ORF names
      C465_15627

Organism names

  • Taxonomic identifier
  • Strain
    • JCM 9100
  • Taxonomic lineage
    Archaea > Methanobacteriati > Methanobacteriota > Stenosarchaea group > Halobacteria > Halobacteriales > Haloferacaceae > Halorubrum > Halorubrum distributum group

Accessions

  • Primary accession
    M0EF87

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain15-265Aspartate/glutamate/uridylate kinase
Region279-308Disordered
Compositional bias289-308Acidic residues

Sequence similarities

Belongs to the acetylglutamate kinase family. LysZ subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    308
  • Mass (Da)
    30,552
  • Last updated
    2013-04-03 v1
  • MD5 Checksum
    35F8993C2AF3AA1699BA041318D3A88C
MTGESEAASGAEPPVVVKVGGAKAVDPAGAVGDVAHLAANGRAVVVVHGGSTVVDETLERLGIEPEYVESASGVTGRFTDAETMEAFAMAMAGKLNTELTAQFRSAGVDAVGLSGVDGGLLAGPRKSAVRVVEDGKKKIRRGDHSGTIESVNADLLAGLLDDGYTPVVSPPMAGDEGDGEVTPVNADADRAAAAVAGALGADLVLLTDVSGVYADPDDPETRIDSAATPGELAAVEDAAEGFMGKKVMAATEALEGGSGRVVIADANVRDPVVAALGGEGTTIERSALADDDAGGETGDADETEGIDA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias289-308Acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AOJM01000081
EMBL· GenBank· DDBJ
ELZ45064.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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