M0EBG7 · M0EBG7_9EURY
- ProteinDNA-directed RNA polymerase subunit Rpo1N
- Generpo1N
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids970 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Catalytic activity
- RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate
Cofactor
Protein has several cofactor binding sites:
Note: Binds at least 2 Zn2+ per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 54 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 57 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 64 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 67 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 94 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 97 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 141 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 144 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 519 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 521 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 523 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | DNA-directed RNA polymerase complex | |
Molecular Function | DNA binding | |
Molecular Function | magnesium ion binding | |
Molecular Function | plastid single subunit type RNA polymerase activity | |
Molecular Function | RNA polymerase I activity | |
Molecular Function | RNA polymerase II activity | |
Molecular Function | RNA polymerase III activity | |
Molecular Function | RNA polymerase IV activity | |
Molecular Function | RNA polymerase V activity | |
Molecular Function | zinc ion binding |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA-directed RNA polymerase subunit Rpo1N
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Methanobacteriati > Methanobacteriota > Stenosarchaea group > Halobacteria > Halobacteriales > Haloferacaceae > Halorubrum > Halorubrum distributum group
Accessions
- Primary accessionM0EBG7
Proteomes
Subcellular Location
Interaction
Subunit
Part of the RNA polymerase complex.
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 269-573 | RNA polymerase N-terminal | |||
Compositional bias | 933-946 | Basic and acidic residues | |||
Region | 933-970 | Disordered | |||
Sequence similarities
Belongs to the RNA polymerase beta' chain family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length970
- Mass (Da)108,015
- Last updated2013-04-03 v1
- MD5 Checksum61291E076C7D2B39759DBEB85EBE1497
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 933-946 | Basic and acidic residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AOJM01000080 EMBL· GenBank· DDBJ | ELZ45141.1 EMBL· GenBank· DDBJ | Genomic DNA |